Assessment of Monitoring and Management Practices of Antipsychotic-Induced Hyperprolactinemia at a Medical City in Riyadh, Saudi Arabia: A Retrospective Cohort Study
CONCLUSION: It is imperative to conduct a baseline check of prolactin levels before commencing any antipsychotic therapy. Similarly, routine prolactin level monitoring is recommended regardless of symptoms in patients treated with antipsychotics with a possible prolactin-raising effect. Adherence to evidence-based treatment guidelines can improve patient quality of life and therapeutic compliance.PMID:38485677 | DOI:10.2174/0115748863280407240305070905 (Source: Current Drug Safety)
Source: Current Drug Safety - March 14, 2024 Category: Drugs & Pharmacology Authors: Zahra Hussain Alshabeeb Bashayr Alsuwayni Omar Alshargi Ahmed H Abdelazeem Source Type: research
Assessment of Monitoring and Management Practices of Antipsychotic-Induced Hyperprolactinemia at a Medical City in Riyadh, Saudi Arabia: A Retrospective Cohort Study
CONCLUSION: It is imperative to conduct a baseline check of prolactin levels before commencing any antipsychotic therapy. Similarly, routine prolactin level monitoring is recommended regardless of symptoms in patients treated with antipsychotics with a possible prolactin-raising effect. Adherence to evidence-based treatment guidelines can improve patient quality of life and therapeutic compliance.PMID:38485677 | DOI:10.2174/0115748863280407240305070905 (Source: Current Drug Safety)
Source: Current Drug Safety - March 14, 2024 Category: Drugs & Pharmacology Authors: Zahra Hussain Alshabeeb Bashayr Alsuwayni Omar Alshargi Ahmed H Abdelazeem Source Type: research
Long-acting second-generation injectable antipsychotics for the maintenance treatment of bipolar disorder: a narrative review
Expert Opin Pharmacother. 2024 Mar 11:1-5. doi: 10.1080/14656566.2024.2329743. Online ahead of print.ABSTRACTINTRODUCTION: Non-adherence to medication significantly affects bipolar disorder outcomes. Long-Acting Injectable antipsychotics show promise by ensuring adherence and averting relapses.AREAS COVERED: This narrative review sought to evaluate the efficacy of second-generation injectable antipsychotics in bipolar disorder through searches in Embase, MEDLINE, and PsycInfo for randomized controlled trials and mirror-image studies.Risperidone and aripiprazole Long-Acting Injectables demonstrated effectiveness in preventi...
Source: Expert Opinion on Pharmacotherapy - March 11, 2024 Category: Drugs & Pharmacology Authors: Jean-Baptiste Belge Bernard G C C Sabbe Source Type: research
A case report of LAI two injection start in a 16-year-old adolescent with severe manic episode and comorbid cannabinoid use disorder
Asian J Psychiatr. 2024 Mar 4;94:103992. doi: 10.1016/j.ajp.2024.103992. Online ahead of print.ABSTRACTThere is a lack of randomized clinical trials and few studies regarding long-acting injectable antipsychotics (LAIs) in adolescents. Non-adherence, aggressiveness, comorbid substance use disorder and lack of insight may represent the main reasons for starting LAIs. Hereby we describe a 16-year-old male adolescent subject with bipolar type I disorder and comorbid cannabinoid use disorder, successfully treated with two-injection start regimen of LAI aripiprazole. Two-injection start regime of aripiprazole could represent an...
Source: Asian Journal of Psychiatry - March 10, 2024 Category: Psychiatry Authors: Laura Orsolini Sofia Pacini Biagiotti Lorenzo Maria Martino Umberto Volpe Source Type: research
Treatment of antipsychotic-induced hyperprolactinemia: an umbrella review of systematic reviews and meta-analyses
ConclusionAdjunctive dopamine agonists have been proven to be effective and safe for the treatment of antipsychotic-induced hyperprolactinemia. Among the researched treatments, adding aripiprazole may be the most appropriate. (Source: Frontiers in Psychiatry)
Source: Frontiers in Psychiatry - March 5, 2024 Category: Psychiatry Source Type: research
Genotoxic and genoprotective effects of some antipsychotic drugs, methylphenidate and atomoxetine on human lymphocytes and HepG2 cells
CONCLUSIONS: As a result, the genotoxicity of the drugs was found to be dose-dependent, and all drugs showed a genoprotective effect on DNA-damaged cells.PMID:38436168 | DOI:10.26355/eurrev_202402_35456 (Source: Pharmacological Reviews)
Source: Pharmacological Reviews - March 4, 2024 Category: Drugs & Pharmacology Authors: S K Sezer S Yuksel I Ucuz Source Type: research
Genotoxic and genoprotective effects of some antipsychotic drugs, methylphenidate and atomoxetine on human lymphocytes and HepG2 cells
CONCLUSIONS: As a result, the genotoxicity of the drugs was found to be dose-dependent, and all drugs showed a genoprotective effect on DNA-damaged cells.PMID:38436168 | DOI:10.26355/eurrev_202402_35456 (Source: European Review for Medical and Pharmacological Sciences)
Source: European Review for Medical and Pharmacological Sciences - March 4, 2024 Category: Drugs & Pharmacology Authors: S K Sezer S Yuksel I Ucuz Source Type: research
Mechanisms of adverse mammary effect induced by olanzapine and therapeutic interventions in rat model
CONCLUSIONS: These results shed light on the previously overlooked effect of olanzapine on mammary development and present experimental evidence to support current clinical management strategies of antipsychotic induced side effects in the breast.PMID:38437955 | DOI:10.1016/j.taap.2024.116876 (Source: Toxicology and Applied Pharmacology)
Source: Toxicology and Applied Pharmacology - March 4, 2024 Category: Toxicology Authors: Yingyue Dong Xiaozhe Sun Hanxiao Li Chunmiao Han Yue Zhang Huiru Ding Lisha Xia Huamin Wang Shaomin Yang Lingzi Xu Guoheng Xu Source Type: research
Genotoxic and genoprotective effects of some antipsychotic drugs, methylphenidate and atomoxetine on human lymphocytes and HepG2 cells
CONCLUSIONS: As a result, the genotoxicity of the drugs was found to be dose-dependent, and all drugs showed a genoprotective effect on DNA-damaged cells.PMID:38436168 | DOI:10.26355/eurrev_202402_35456 (Source: Pharmacological Reviews)
Source: Pharmacological Reviews - March 4, 2024 Category: Drugs & Pharmacology Authors: S K Sezer S Yuksel I Ucuz Source Type: research
Genotoxic and genoprotective effects of some antipsychotic drugs, methylphenidate and atomoxetine on human lymphocytes and HepG2 cells
CONCLUSIONS: As a result, the genotoxicity of the drugs was found to be dose-dependent, and all drugs showed a genoprotective effect on DNA-damaged cells.PMID:38436168 | DOI:10.26355/eurrev_202402_35456 (Source: European Review for Medical and Pharmacological Sciences)
Source: European Review for Medical and Pharmacological Sciences - March 4, 2024 Category: Drugs & Pharmacology Authors: S K Sezer S Yuksel I Ucuz Source Type: research
Mechanisms of adverse mammary effect induced by olanzapine and therapeutic interventions in rat model
CONCLUSIONS: These results shed light on the previously overlooked effect of olanzapine on mammary development and present experimental evidence to support current clinical management strategies of antipsychotic induced side effects in the breast.PMID:38437955 | DOI:10.1016/j.taap.2024.116876 (Source: Toxicology and Applied Pharmacology)
Source: Toxicology and Applied Pharmacology - March 4, 2024 Category: Toxicology Authors: Yingyue Dong Xiaozhe Sun Hanxiao Li Chunmiao Han Yue Zhang Huiru Ding Lisha Xia Huamin Wang Shaomin Yang Lingzi Xu Guoheng Xu Source Type: research
Genotoxic and genoprotective effects of some antipsychotic drugs, methylphenidate and atomoxetine on human lymphocytes and HepG2 cells
CONCLUSIONS: As a result, the genotoxicity of the drugs was found to be dose-dependent, and all drugs showed a genoprotective effect on DNA-damaged cells.PMID:38436168 | DOI:10.26355/eurrev_202402_35456 (Source: European Review for Medical and Pharmacological Sciences)
Source: European Review for Medical and Pharmacological Sciences - March 4, 2024 Category: Drugs & Pharmacology Authors: S K Sezer S Yuksel I Ucuz Source Type: research
