Safety outcomes of antipsychotics classes in drug-na ïve patients with first-episode schizophrenia: A nationwide cohort study in South Korea
CONCLUSIONS: The risk of drug-induced parkinsonism was significantly higher with risperidone than with aripiprazole. Although olanzapine is known for its metabolic risk, there were no significant differences in risk between the other pairs.PMID:38128353 | DOI:10.1016/j.ajp.2023.103857 (Source: Asian Journal of Psychiatry)
Source: Asian Journal of Psychiatry - December 21, 2023 Category: Psychiatry Authors: Dong Yun Lee Chungsoo Kim Dong Han Yu Rae Woong Park Source Type: research

Comparative effectiveness of aripiprazole and olanzapine on neurocognitive profile of patients with schizophrenia
CONCLUSION: The study concludes that aripiprazole and olanzapine have strong potential to improve specific domains of neurocognitive profile.PMID:38108052 | PMC:PMC10725211 | DOI:10.4103/indianjpsychiatry.indianjpsychiatry_303_23 (Source: Indian Journal of Psychiatry)
Source: Indian Journal of Psychiatry - December 18, 2023 Category: Psychiatry Authors: Sanya Sharma Ajeet Sidana Shivangi Mehta Manoj Kumar Bajaj Source Type: research

Oral and long-acting injectable antipsychotic discontinuation and relationship to side effects in people with first episode psychosis: a longitudinal analysis of electronic health record data
CONCLUSION: Earlier treatment discontinuation associated with sexual or extrapyramidal side effects could be related to their rapid onset and poor tolerability. Later treatment discontinuation associated with clozapine and PP1M could be related to the relative efficacy of these treatments. These findings merit consideration when selecting antipsychotic therapy for people with FEP.PMID:38107162 | PMC:PMC10725124 | DOI:10.1177/20451253231211575 (Source: Adv Data)
Source: Adv Data - December 18, 2023 Category: Epidemiology Authors: Rashmi Patel Aimee Brinn Jessica Irving Jaya Chaturvedi Shanmukha Gudiseva Christoph U Correll Paolo Fusar-Poli Philip McGuire Source Type: research

Comparative effectiveness of aripiprazole and olanzapine on neurocognitive profile of patients with schizophrenia
CONCLUSION: The study concludes that aripiprazole and olanzapine have strong potential to improve specific domains of neurocognitive profile.PMID:38108052 | PMC:PMC10725211 | DOI:10.4103/indianjpsychiatry.indianjpsychiatry_303_23 (Source: Indian Journal of Psychiatry)
Source: Indian Journal of Psychiatry - December 18, 2023 Category: Psychiatry Authors: Sanya Sharma Ajeet Sidana Shivangi Mehta Manoj Kumar Bajaj Source Type: research