Impact of CADILLAC and GRACE risk scores on short- and long-term clinical outcomes in patients with acute myocardial infarction
CONCLUSION: Both CADILLAC and GRACE risk scores were predictive for short- and long-term mortality and MACE rates in a contemporary cohort of acute MI patients undergoing primary percutaneous coronary intervention.PMID:33947628 | DOI:10.1016/j.jjcc.2021.04.005 (Source: Journal of Cardiology)
Source: Journal of Cardiology - May 5, 2021 Category: Cardiology Authors: Takanori Sato Yuichi Saito Tadahiro Matsumoto Daichi Yamashita Kan Saito Shinichi Wakabayashi Hideki Kitahara Koichi Sano Yoshio Kobayashi Source Type: research
Impact of CADILLAC and GRACE risk scores on short- and long-term clinical outcomes in patients with acute myocardial infarction
CONCLUSION: Both CADILLAC and GRACE risk scores were predictive for short- and long-term mortality and MACE rates in a contemporary cohort of acute MI patients undergoing primary percutaneous coronary intervention.PMID:33947628 | DOI:10.1016/j.jjcc.2021.04.005 (Source: Journal of Cardiology)
Source: Journal of Cardiology - May 5, 2021 Category: Cardiology Authors: Takanori Sato Yuichi Saito Tadahiro Matsumoto Daichi Yamashita Kan Saito Shinichi Wakabayashi Hideki Kitahara Koichi Sano Yoshio Kobayashi Source Type: research
Intravenous abciximab as a rescue therapy for immediate reocclusion after successful mechanical thrombectomy in acute ischemic stroke patients
Conclusions - Our results underscore a key role for platelet aggregation and the potential of Glycoprotein IIb/IIIa antagonists as a rescue therapy in post-MT immediate reocclusion.PMID:33840346 | DOI:10.1080/09537104.2021.1894326 (Source: Platelets)
Source: Platelets - April 12, 2021 Category: Hematology Authors: Fran çois Delvoye Stephane Loyau Julien Labreuche Guillaume Taylor Benjamin Maier Michel Piotin Raphael Blanc Simon Escalard Lucas Di Meglio Malek Ben Maacha Hocine Redjem Stanislas Smajda Gabriele Ciccio Sol ène Hébert Candice Sabben Martine Jandrot-P Source Type: research
Delayed thrombocytopenia following administration of abciximab: Pharmacovigilance survey and literature review
CONCLUSION: Delayed thrombocytopenia, probably due to immune reaction, is a possible life-threatening adverse effect of ABX with a mean TTO of 9 days, supporting the recommendation of a platelet count monitoring during at least two weeks. This recommendation was added to the abcximab SmPC in 2019.PMID:33726948 | DOI:10.1016/j.therap.2021.02.006 (Source: Therapie)
Source: Therapie - March 17, 2021 Category: Psychiatry & Psychology Authors: Louis Vincent Delphine Bourneau-Martin Ana ïs Maurier Marina Babin St éphane Delepine Dominique Helley Aur élie Grandvuillemin Laurence Lagarce Agn ès Lillo-Le Louët Marie Briet Source Type: research
Delayed thrombocytopenia following administration of abciximab: Pharmacovigilance survey and literature review
CONCLUSION: Delayed thrombocytopenia, probably due to immune reaction, is a possible life-threatening adverse effect of ABX with a mean TTO of 9 days, supporting the recommendation of a platelet count monitoring during at least two weeks. This recommendation was added to the abcximab SmPC in 2019.PMID:33726948 | DOI:10.1016/j.therap.2021.02.006 (Source: Therapie)
Source: Therapie - March 17, 2021 Category: Psychiatry & Psychology Authors: Louis Vincent Delphine Bourneau-Martin Ana ïs Maurier Marina Babin St éphane Delepine Dominique Helley Aur élie Grandvuillemin Laurence Lagarce Agn ès Lillo-Le Louët Marie Briet Source Type: research
Delayed thrombocytopenia following administration of abciximab: Pharmacovigilance survey and literature review
CONCLUSION: Delayed thrombocytopenia, probably due to immune reaction, is a possible life-threatening adverse effect of ABX with a mean TTO of 9 days, supporting the recommendation of a platelet count monitoring during at least two weeks. This recommendation was added to the abcximab SmPC in 2019.PMID:33726948 | DOI:10.1016/j.therap.2021.02.006 (Source: Therapie)
Source: Therapie - March 17, 2021 Category: Psychiatry & Psychology Authors: Louis Vincent Delphine Bourneau-Martin Ana ïs Maurier Marina Babin St éphane Delepine Dominique Helley Aur élie Grandvuillemin Laurence Lagarce Agn ès Lillo-Le Louët Marie Briet Source Type: research
Delayed thrombocytopenia following administration of abciximab: Pharmacovigilance survey and literature review
CONCLUSION: Delayed thrombocytopenia, probably due to immune reaction, is a possible life-threatening adverse effect of ABX with a mean TTO of 9 days, supporting the recommendation of a platelet count monitoring during at least two weeks. This recommendation was added to the abcximab SmPC in 2019.PMID:33726948 | DOI:10.1016/j.therap.2021.02.006 (Source: Therapie)
Source: Therapie - March 17, 2021 Category: Psychiatry & Psychology Authors: Louis Vincent Delphine Bourneau-Martin Ana ïs Maurier Marina Babin St éphane Delepine Dominique Helley Aur élie Grandvuillemin Laurence Lagarce Agn ès Lillo-Le Louët Marie Briet Source Type: research
Delayed thrombocytopenia following administration of abciximab: Pharmacovigilance survey and literature review
CONCLUSION: Delayed thrombocytopenia, probably due to immune reaction, is a possible life-threatening adverse effect of ABX with a mean TTO of 9 days, supporting the recommendation of a platelet count monitoring during at least two weeks. This recommendation was added to the abcximab SmPC in 2019.PMID:33726948 | DOI:10.1016/j.therap.2021.02.006 (Source: Therapie)
Source: Therapie - March 17, 2021 Category: Psychiatry & Psychology Authors: Louis Vincent Delphine Bourneau-Martin Ana ïs Maurier Marina Babin St éphane Delepine Dominique Helley Aur élie Grandvuillemin Laurence Lagarce Agn ès Lillo-Le Louët Marie Briet Source Type: research
Efficacy and safety of abciximab versus tirofiban in addition to ticagrelor in STEMI patients undergoing primary percutaneous intervention.
The objectives were to assess the efficacy and safety of abciximab versus tirofiban in patients with ST-elevation acute myocardial infarction (STEMI) undergoing primary percutaneous coronary intervention (PPCI) and pretreated with ticagrelor, and to identify independent predictor factors of efficacy, bleeding and platelet drop. Three hundred sixty-two patients were divided by GPI administered. Clinical, laboratory, angiographic and outcome characteristics were compared. The primary objective was a composite efficacy endpoint (death from any cause, nonfatal myocardial infarction and nonfatal stroke) at 30 days. The seconda...
Source: Platelets - February 10, 2021 Category: Hematology Tags: Platelets Source Type: research
Effects of intracoronary antithrombotics on ventricular function: A comparison of tenecteplase versus abciximab during primary percutaneous intervention in myocardial infarction.
PMID: 33438179 [PubMed - as supplied by publisher] (Source: Cardiology Journal)
Source: Cardiology Journal - January 13, 2021 Category: Cardiology Authors: Morales-Ponce FJ, González-Pérez P, Blasco-Turrión S, Sánchez-Brotons JA, Collado-Moreno C, Martínez-Romero P, Martínez-Morentín E, Caro-Mateo P Tags: Cardiol J Source Type: research
TEG PlateletMapping assay results may be misleading in the presence of cold stored platelets.
DISCUSSION: The PlateletMapping MAFIBRIN and MAADP test results may be misleadingly high with CSPs, particularly with the TEG 5000 analyzer, most likely due to constitutive activation of GPIIb/IIIa on CSPs during storage. TEG PlateletMapping results should be interpreted with caution following CSP transfusion.
PMID: 32478898 [PubMed - as supplied by publisher] (Source: Transfusion)
Source: Transfusion - May 31, 2020 Category: Hematology Authors: Scorer TG, FitzGibbon L, Aungraheeta R, Sharma U, Peltier GC, McIntosh CS, Reddoch-Cardenas KM, Meyer A, Cap AP, Mumford AD Tags: Transfusion Source Type: research
[Reports] Platelets from HIV-infected individuals on antiretroviral drug therapy with poor CD4+ T cell recovery can harbor replication-competent HIV despite viral suppression
In addition to hemostasis, human platelets have several immune functions and interact with infectious pathogens including HIV in vitro. Here, we report that platelets from HIV-infected individuals on combined antiretroviral drug therapy (ART) with low blood CD4+ T cell counts (<350 cells/μl) contained replication-competent HIV despite viral suppression. In vitro, human platelets harboring HIV propagated the virus to macrophages, a process that could be prevented with the biologic abciximab, an anti–integrin αIIb/β3 Fab. Furthermore, in our cohort, 88% of HIV-infected individuals on ART with viral sup...
Source: Science Translational Medicine - March 17, 2020 Category: Biomedical Science Authors: Real, F., Capron, C., Sennepin, A., Arrigucci, R., Zhu, A., Sannier, G., Zheng, J., Xu, L., Masse, J.-M., Greffe, S., Cazabat, M., Donoso, M., Delobel, P., Izopet, J., Eugenin, E., Gennaro, M. L., Rouveix, E., Cramer Borde, E., Bomsel, M. Tags: Reports Source Type: research
Adjuvant antithrombotic therapy in ST-elevation myocardial infarction: Contemporaneous Portuguese cross-sectional data
ConclusionsIn 2016, according to data from these national registries, almost all patients with STEMI were treated with aspirin and 76% with dual antiplatelet agents, mostly clopidogrel. GP IIb/IIIa inhibitors were used in few patients, and UFH was the most prevalent parenteral anticoagulant drug.ResumoIntroduçãoO tratamento do enfarte agudo do miocárdio com elevação do segment ST (EAMCSST) baseia-se na ativação da via verde coronária, na administração de terapêutica médica adjuvante e na reperfusão através de angioplastia primária percutânea. A angioplastia primária constitui o tratamento de primeira linha...
Source: Revista Portuguesa de Cardiologia - February 21, 2020 Category: Cardiology Source Type: research
