Inhibitors of Gq signalling down-regulate β-catenin expression & amp; function in human colon cancer cells

CONCLUSIONS: The results of this study further support the positive role of Gq signalling in regulating β-catenin expression and function and may provide a new means of preventing β-catenin-mediated carcinogenesis by blocking heterotrimeric G proteins.PMID:35645087 | DOI:10.4103/ijmr.IJMR_1370_19

Source: The Indian Journal of Medical Research - June 1, 2022 Category: Biomedical Science Authors: Nasim Forghani S Mahmoud A Najafi Source Type: research