Upregulation of SPI1 during myocardial infarction aggravates cardiac tissue injury and disease progression through activation of the TLR4/NF κB axis

CONCLUSION: This study demonstrated that upregulation of SPI1, caused by reduced DNA methylation, augmented development of myocardial infarction by activating the TLR4/NFκB axis.PMID:35559389 | PMC:PMC9091125

Source: American Journal of Translational Research - May 13, 2022 Category: Research Authors: Zhengling Liu Shuai Huang Source Type: research