Changes in transepithelial electrical resistance and intracellular ion concentration in TGF- β-induced epithelial-mesenchymal transition of retinal pigment epithelial cells

CONCLUSION: TGF-β1 and TGF-β2 disrupted the ARPE-19 cell monolayer, disturbed TJs integrity, downregulated TEER values, and changed intracellular ion permeability. These findings might help further understand the EMT of RPE cells during PVR.PMID:35559413 | PMC:PMC9091112

Source: American Journal of Translational Research - May 13, 2022 Category: Research Authors: Minli Wang Jiayi Wei Hui Li Fang Wang Source Type: research