NADPH oxidase-induced activation of transforming growth factor-beta-1 causes neuropathy by suppressing antioxidant signaling pathways in alcohol use disorder

In conclusion, this study significantly extends our understanding of the pathophysiology of AUD and provides a unique insight for developing various therapeutic interventions by activating antioxidant signaling pathways for the treatment of AUD-induced neurological complications.PMID:35584723 | DOI:10.1016/j.neuropharm.2022.109136

Source: Neuropharmacology - May 18, 2022 Category: Drugs & Pharmacology Authors: Saurav Bhowmick Saleena Alikunju P M Abdul-Muneer Source Type: research