Tanshinone IIA attenuates elastase-induced AAA in rats via inhibition of MyD88-dependent TLR-4 signaling.

Conclusions: Tan IIA attenuates elastase-induced AAA in rats possibly via the inhibition of MyD88-dependent TLR-4 signaling, which may be one potential explanation of why Tan IIA inhibits AAA development through multiple effects.
PMID: 24429329 [PubMed - in process]

Source: VASA. Zeitschrift fur Gefasskrankheiten. Journal for Vascular Diseases - January 1, 2014 Category: Surgery Authors: Shang T, Ran F, Qiao Q, Liu Z, Liu CJ Tags: Vasa Source Type: research