Duffy antigen / receptor for chemokines correlates with inflammatory reaction in rats with venous hypertension: implication for the pathogenesis of primary chronic venous disease.

Conclusions: A rat AVF model which can maintain venous hypertension for at least 42 days is competent for researching the pathogenesis of CVD. DARC, which plays a role in the inflammation of skin tissue under venous hypertension, may become a new molecular target for diagnosis and treatment of CVD at a very early stage.
PMID: 24429330 [PubMed - in process]

Source: VASA. Zeitschrift fur Gefasskrankheiten. Journal for Vascular Diseases - January 1, 2014 Category: Surgery Authors: Huang W, Qin W, Lv L, Deng H, Zhang H, Zhang J, Zhang L Tags: Vasa Source Type: research