YY1 as a promoter regulating the circ_0001946/miR-671-5p/EGFR axis to promote chemotherapy resistance in breast cancer cells

CONCLUSION: Circ_0001946 absorbs miR-671-5p to target EGFR to promote the growth and malignant invasion of drug-resistant BC cells, thereby increasing the resistance to tamoxifen. This effect of circ_0001946 may be achieved by transcriptional activation of YY1.PMID:35559420 | PMC:PMC9091114
Source: American Journal of Translational Research - Category: Research Authors: Source Type: research