Docosahexaenoic acid ester of phloridzin reduces inflammation and insulin resistance via AMPK

CONCLUSION: The effects of PZ-DHA on insulin resistance in C2C12 myotubes may be mediated by the LKB1-AMPK signaling pathway. Hence, PZ-DHA is a promising therapeutic agent for insulin resistance in type 2 diabetes.PMID:35585811 | DOI:10.2174/1381612828666220518102440

Source: Current Pharmaceutical Design - May 19, 2022 Category: Drugs & Pharmacology Authors: Jingqing Chen Zhenlong Wu Jin Wang Xuemeng Si Rui Zhang Tianqi Sun Qiaoyan Dong Wenqing Wu Yefeng Qiu Source Type: research