Human liver single nucleus and single  cell RNA sequencing identify a hepatocellular carcinoma-associated cell-type affecting survival

ConclusionsBy integrating liver single cell, single nucleus, and bulk expression data from multiple cohorts we identified a proliferating cell-type (Prol) enriched in HCC tumors, associated with a decreased overall survival, and linked toTP53 andRB1 somatic mutations.
Source: Genome Medicine - Category: Genetics & Stem Cells Source Type: research