Pathogenic Viruses Have Evolved to Provoke Cellular Senescence

We present a "decentralized" information processing model that conceptualizes neurodegeneration as a systemic illness, triggered by cytoskeletal pathology. We also discuss strategies for reversing cell-cell fusion, including, TMEM16F inhibitors, calcium channel blockers, senolytics, and tubulin stabilizing agents. Finally, going beyond neurodegeneration, we examine the potential benefit of harnessing fusion as a therapeutic strategy in regenerative medicine. Link: https://doi.org/10.3389/fcimb.2022.845580
Source: Fight Aging! - Category: Research Authors: Tags: Daily News Source Type: blogs