Intravenous immunoglobulin in the management of refractory lupus profundus

Lupus. 2022 May 13:9612033221099873. doi: 10.1177/09612033221099873. Online ahead of print.ABSTRACTLupus profundus, often known as lupus panniculitis, is a rare form of persistent cutaneous lupus erythematosus. It usually manifests as painful plaques or nodules that can ulcerate and cause atrophy and scarring. It may respond to topical treatments and antimalarials, although treatment might be difficult at times, necessitating immunosuppressive medications. A 36-year-old woman from the United Arab Emirates presented with multiple painful disfiguring nodules involving the face and shoulders. The disfiguring skin nodules were resistant to systemic glucocorticoids, hydroxychloroquine, azathioprine, mycophenolate mofetil, and cyclosporine, but they significantly improved with monthly intravenous immunoglobulin over a 6-month period.PMID:35561340 | DOI:10.1177/09612033221099873
Source: Lupus - Category: Rheumatology Authors: Source Type: research