New pyrimidine-5-carbonitrile derivatives as EGFR inhibitors with anticancer and apoptotic activity: Design, molecular modeling and synthesis

New J. Chem., 2022, Accepted Manuscript DOI: 10.1039/D2NJ01451C, PaperIbrahim A. Osman, Rezk R Ayyad, Hazem A. Mahdy In connection with our efforts on the development of new anticancer agents, herein we report the design and synthesis of new small pyrimidine-5-carbonitrile based derivatives. The target pyrimidines were evaluated... The content of this RSS Feed (c) The Royal Society of Chemistry

Source: RSC - New J. Chem. latest articles - May 13, 2022 Category: Chemistry Authors: Ibrahim A. Osman Source Type: research