Evaluation of the RSR 3 screen ICA ™ and 2 screen ICA™ as screening assays for type 1 diabetes in Sweden
Conclusion3 Screen achieved high sensitivity and specificity, suitable for islet cell autoimmunity screening in a healthy population. In the case of 3 Screen positivity, further assays for GADA, IA-2A and ZnT8A are required to check for multiple autoantibody positivity, a hallmark for progression to T1D. In addition, testing for IAA in children below two years of age is warranted.
Source: Acta Diabetologica - Category: Endocrinology Source Type: research
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