Microglia Activation Tracking across Brain Regions over the Development of Neuropathic Pain

Neuropathic pain is a chronic, debilitating condition associated with impaired cognitive, affective and sensory dimensions. One of the mechanisms underlying neuropathic pain is neuroinflammation. Microglia are resident macrophages in the central nervous system and plays an important role in setting neuroinflammation during chronic pain conditions. Microglial mechanisms of pain have been broadly studied in the spinal cord. However, brain mapping of microglial activation over the development of neuropathic pain has not been performed.
Source: The Journal of Pain - Category: Materials Science Authors: Tags: 6 Source Type: research