Homecoming of the estranged GluD channels

Trends Neurosci. 2022 Apr 27:S0166-2236(22)00075-3. doi: 10.1016/j.tins.2022.04.001. Online ahead of print.ABSTRACTA recent paper by Carrillo and colleagues demonstrates that GluD proteins form bona fide ligand-gated ion channels when their intrinsic flexibility is constrained by interactions with protein partners. Therefore, Delta receptors resemble all other members of the ionotropic glutamate receptor family not only by sequence and structural homology, but also by functional dynamics.PMID:35490056 | DOI:10.1016/j.tins.2022.04.001
Source: Trends in Neurosciences - Category: Neuroscience Authors: Source Type: research