Discovery of novel non-steroidal selective glucocorticoid receptor modulators by structure- and IGN-based virtual screening, structural optimization, and biological evaluation

This study reported a group of non-steroidal new-scaffold SGRMs, providing valuable clues for the development of novel anti-inflammatory drugs.PMID:35483323 | DOI:10.1016/j.ejmech.2022.114382

Source: European Journal of Medicinal Chemistry - April 28, 2022 Category: Chemistry Authors: Xueping Hu Jinping Pang Changwei Chen Dejun Jiang Chao Shen Xin Chai Liu Yang Xujun Zhang Lei Xu Sunliang Cui Tingjun Hou Dan Li Source Type: research