Three important short-chain fatty acids (SCFAs) attenuate the inflammatory response induced by 5-FU and maintain the integrity of intestinal mucosal tight junction

5-Fluorouracil (5-FU) is a used chemotherapy drug for cancer, and its main side effect is intestinal mucositis which causes chemotherapy to fail. It was known that short-chain fatty acids (SCFAs) can inhibit i...

Source: BMC Immunology - April 21, 2022 Category: Allergy & Immunology Authors: Xi Yue, Sun Wen, Ding Long-kun, Yan Man, Sun Chang, Zhang Min, Li Shuang-yu, Qian Xin, Ma Jie and Wu Liang Tags: Research Source Type: research