Origin and function of cartilage stem/progenitor cells in osteoarthritis

Nature Reviews Rheumatology 11, 206 (2015). doi:10.1038/nrrheum.2014.200 Authors: Yangzi Jiang & Rocky S. Tuan Articular cartilage is a physiologically non-self-renewing avascular tissue with a singular cell type, the chondrocyte, which functions as the load-bearing surface of the arthrodial joint. Injury to cartilage often progresses spatiotemporally from the articular surface to the subchondral bone, leading to development of degenerative joint
Source: Nature Reviews Rheumatology - Category: Rheumatology Authors: Tags: Review Source Type: research