Fractional anisotropy helps to differentiate the optic nerve impairment between neuromyelitis optica spectrum disorders and multiple sclerosis

ConclusionFA could quantify the characteristics of NMOSD – and MS–related optic nerve impairment. DTI was a simple and effective imaging tool to differentiate between the two.Key Points• NMOSD–related optic nerve impairment is extensive, often greater than half of the optic nerve, with the most significant involvement of the posterior segment of the optic nerve.• MS–related optic nerve impairment is more limited than NMOSD, and anterior and middle optic nerve involvement is common.• Optic nerve DTI is a convenient and effective imaging tool that can help characterize NMOSD and MS.
Source: European Radiology - Category: Radiology Source Type: research