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Here's What '60 Minutes' Didn't Tell You About The 'Miracle' Glioblastoma Treatment

The polio-based cancer therapy pioneered by Duke University researchers and featured on "60 Minutes" is promising, but there are caveats.
Source: Forbes.com Healthcare News - Category: Pharmaceuticals Authors: Source Type: news

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Can devastating viruses such as Zika and Polio really provide new treatment options for people with currently incurable cancers?
Source: Forbes.com Healthcare News - Category: Pharmaceuticals Authors: Source Type: news
22 April 2018, Cairo – This year’s World Immunization Week campaign, celebrated from 24 to 30 April, aims to highlight that protecting entire communities with vaccines protects everyone and so the theme of this year’s campaign is “Protected Together, #VaccinesWork”.  Immunization is one of the most successful and cost-effective health interventions. Studies show that every US$ 1 spent on childhood immunization returns US$ 44 in economic and social benefits.  Immunization protects everyone – from infants to senior citizens – against disabling illnesses, disability a...
Source: WHO EMRO News - Category: Middle East Health Source Type: news
In this study, after confirmation that patients’ NK cells were not impaired in their cytotoxic activity, evaluated against long-term tumor cell lines, we evaluated their interactions with autologous mCRC cells. Molecular and phenotypical evaluation of mCRC cells, expanded in vitro from liver metastasis, showed that they expressed high levels of polio virus receptor and Nectin-2, whereas UL16-binding proteins were less expressed in all tumor samples evaluated. Two different patterns of MICA/B and HLA class I expression on the membrane of mCRC were documented; approximately half of mCRC patients expressed high levels o...
Source: Journal of Immunotherapy - Category: Allergy & Immunology Tags: Basic Studies Source Type: research
Abstract Gemin3, also known as DDX20 or DP103, is a DEAD-box RNA helicase which is involved in more than one cellular process. Though RNA unwinding has been determined in vitro, it is surprisingly not required for all of its activities in cellular metabolism. Gemin3 is an essential gene, present in Amoeba and Metazoa. The highly conserved N-terminus hosts the helicase core, formed of the helicase- and DEAD-domains, which, based on crystal structure determination, have key roles in RNA binding. The C-terminus of Gemin3 is highly divergent between species and serves as the interaction site for several accessory fact...
Source: Biochemical Society Transactions - Category: Biochemistry Authors: Tags: Biochem Soc Trans Source Type: research
The Department of Health and Human Services (HHS) announced on January 31, 2018, that Dr. Brenda Fitzgerald would resign as the Director of the Centers for Disease Control and Prevention (CDC). The statement read, “Dr. Fitzgerald owns certain complex financial interests that have imposed a broad recusal limiting her ability to complete all of her duties as the CDC Director. Due to the nature of these financial interests, Dr. Fitzgerald could not divest from them in a definitive time period.” The decision came a day after Politico reported that she bought stock in a large tobacco company within a month of start...
Source: Public Policy Reports - Category: Biology Authors: Source Type: news
January 19, 2018It ’s notallbad news.When we set out to compile our annual list of global health issues to watch this year, it seemed like all bad news. And true, that ’s often what we deal with in global health—the problems that need tackling, the suffering we can help alleviate.But then stories and columns likethis one cheer us up. They remind us that no matter how complicated and frustrating our work may get, fighting back against poverty and inequality works.There are and always will be global health challenges to face. But there ’s boundless hope, too. And a field full of determined health work...
Source: IntraHealth International - Category: International Medicine & Public Health Authors: Source Type: news
Just as the President of the United States undergoes an annual checkup and physical every year, it makes sense that they should undergo an annual checkup for their mental health too. Since mental health is of equal importance to one’s physical health, it makes little sense to ignore it and pretend it’s not important. Or worse, to act as though a person’s mental health either doesn’t exist or can’t be objectively measured. It’s time for the President to undergo annual mental health checkups, coinciding with their physical exams. It goes without saying that most actual smart people don&rs...
Source: World of Psychology - Category: Psychiatry & Psychology Authors: Tags: Brain and Behavior General Mental Health and Wellness Minding the Media Policy and Advocacy Psychology Donald Trump fitness for office litmus test mental exam Mental Fitness president's fitness president's mental health should we Source Type: blogs
We examined associations between mortality and accelerometer-measured PA using age-relevant intensity cutpoints in older women of various ethnicities. The results support the hypothesis that higher levels of accelerometer-measured PA, even when below the moderate-intensity threshold recommended in current guidelines, are associated with lower all-cause and CVD mortality in women aged 63 to 99. Our findings expand on previous studies showing that higher self-reported PA reduces mortality in adults aged 60 and older, specifically in older women, and at less than recommended amounts. Moreover, our findings challenge th...
Source: Fight Aging! - Category: Research Authors: Tags: Newsletters Source Type: blogs
My attention was drawn today to a recently published presentation by James Peyer. He heads up Apollo Ventures, one of the new crop of investment concerns focused on funding companies that are developing means to treat aging. These include the Longevity Fund, first out of the gate some years ago, as well as Juvenescence and the Methuselah Fund, created this year, and a repurposing of existing funds, such as Michael Greve's Kizoo ventures. Apollo Ventures is the source of the Geroscience online magazine that helps to advance and explain the position taken on aging by this group; this is something that more investors should d...
Source: Fight Aging! - Category: Research Authors: Tags: Healthy Life Extension Community Source Type: blogs
(Solving Kids' Cancer) A Phase 1 clinical trial leveraging the re-engineered polio virus is now open for enrollment to children 12 years and older at the Preston Robert Tisch Brain Tumor Center, Duke University Medical Center. After years of following the progress of this promising therapy against adult glioblastoma and working with the research team on behalf of children, Solving Kids' Cancer teamed up with The Andrew McDonough B+ Foundation to help move this forward in a trial for pediatric brain tumor patients.
Source: EurekAlert! - Cancer - Category: Cancer & Oncology Source Type: news
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