Here's What '60 Minutes' Didn't Tell You About The 'Miracle' Glioblastoma Treatment

The polio-based cancer therapy pioneered by Duke University researchers and featured on "60 Minutes" is promising, but there are caveats.
Source: Healthcare News - Category: Pharmaceuticals Authors: Source Type: news

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Abstract Preoperative oral care is helpful to prevent postoperative complications in patients who are undergoing esophagectomy. Here, we report the case of an 81-year-old Japanese man with an upper limb disability caused by post-polio syndrome who was receiving neoadjuvant chemotherapy for esophageal cancer. He had poor oral health status and developed oral complications as a side effect of chemotherapy. He could not brush his teeth by himself. However, infection control by oral care provided by an interprofessional collaboration successfully improved his oral hygiene, and his follow-up involved no severe complica...
Source: Acta Med Okayama - Category: Universities & Medical Training Authors: Tags: Acta Med Okayama Source Type: research
Conclusion: Poliovirus sequences in the human genome may contribute to programmed cell death and lysis of colorectal cancer cells. A recombinant poliovirus, incapable of reverting to neurovirulence, might be given orally at intervals as a colorectal cancer vaccine to prevent colorectal cancer.
Source: Cancer Genomics and Proteomics - Category: Cancer & Oncology Authors: Tags: Article Source Type: research
nin To date, no targeted drugs, antibodies or combinations of chemotherapeutics have been demonstrated to be more efficient than temozolomide, or to increase efficacy of standard therapy (surgery, radiotherapy, temozolomide, steroid dexamethasone). According to recent phase III trials, standard therapy may ensure a median overall survival of up to 18–20 months for adult patients with newly diagnosed glioblastoma. These data explain a failure of positive non-controlled phase II trials to predict positive phase III trials and should result in revision of the landmark Stupp trial as a historical control for medi...
Source: Cancers - Category: Cancer & Oncology Authors: Tags: Review Source Type: research
Background/Aim: Polio is predominantly an enteric viral infection that was progressively eradicated in the United States after the introduction of polio vaccine in the early 1950s. U.S. colorectal cancer rates have dropped steadily for individuals born between 1890 and 1950, but have been increasing for every generation born since 1950. Moreover, the lowest worldwide age adjusted rates of colorectal cancer in 2012 were in sub-Saharan Africa, Gambia and Mozambique, where polio has not been eradicated. In the current study, poliomyelitis incidence in US states before the introduction of polio vaccine was analyzed. Materials ...
Source: In Vivo - Category: Research Authors: Tags: Clinical Studies Source Type: research
There’s a very big difference between simple and easy—especially when it comes to global health. It’s simple to eradicate polio—just get all children are vaccinated. It’s simple to reduce nighttime malaria infections—make sure everyone in malaria-endemic areas sleeps under a bed net. But none of that is easy. The tension between simple and easy is at play when it comes to eradicating poverty in the developing world too, as the Bill &Melinda Gates Foundation makes clear in its second annual Goalkeepers Data Report. In a conversation with TIME, Bill Gates points to two recent waves of ...
Source: TIME: Health - Category: Consumer Health News Authors: Tags: Uncategorized onetime public health Source Type: news
(MedPage Today) -- This week's topics include hospital at home, using a virus to treat brain cancer, updated osteoporosis guidelines, and an artificial pancreas in hospitalized patients
Source: MedPage Today Nephrology - Category: Urology & Nephrology Source Type: news
Some 21% of patients with advanced brain cancer treated with a modified polio vaccine were alive after three years, compared with 4% of patients with similar tumors who received standard therapies, U.S. researchers said on Tuesday.Reuters Health Information
Source: Medscape Medical News Headlines - Category: Consumer Health News Tags: Medscape Today News Source Type: news
An ancient scourge -- the polio virus -- may be an unexpected friend to people battling one of the deadliest brain cancers, new research shows.
Source: WebMD Health - Category: Consumer Health News Source Type: news
Doctors using the polio virus to treat aggressive brain tumors called glioblastomas report promising results. Sen. John McCain has this type of cancer, and so did Sen. Ted Kennedy. Of 61 patients treated in one study, 21 percent were still alive at the three-year mark. That's compared with just four percent of patients who received standard cancer treatment. Dr. David Agus, director of USC Norris Westside Cancer Center, joins "CBS This Morning" to discuss the treatment. He also weighs in on a study that showed flight attendants had a higher cancer prevalence than the general population.
Source: Health News: - Category: Consumer Health News Source Type: news
Survival was better than expected for patients in a small study at Duke University who were given genetically modified poliovirus, which helped their bodies attack the cancer, doctors report.
Source: the Mail online | Health - Category: Consumer Health News Source Type: news
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