Machine learning and semi-targeted lipidomics identify distinct serum lipid signatures in hospitalized COVID-19-positive and COVID-19-negative patients

Lipids are involved in the interaction between viral infection and the host metabolic and immunological responses. Several studies comparing the lipidome of COVID-19-positive hospitalized patients vs. healthy subjects have already been reported. It is largely unknown, however, whether these differences are specific to this disease. The present study compared the lipidomic signature of hospitalized COVID-19-positive patients with that of healthy subjects, as well as with COVID-19-negative patients hospitalized for other infectious/inflammatory diseases.

Source: Metabolism - Clinical and Experimental - April 2, 2022 Category: Biomedical Science Authors: Helena Casta ñé, Simona Iftimie, Gerard Baiges-Gaya, Elisabet Rodríguez-Tomàs, Andrea Jiménez-Franco, Ana Felisa López-Azcona, Pedro Garrido, Antoni Castro, Jordi Camps, Jorge Joven Source Type: research