Changes in the endocannabinoid signaling system in CNS structures of TDP-43 transgenic mice: relevance for a neuroprotective therapy in TDP-43-related disorders

In conclusion, our data support the idea that the endocannabinoid signaling system, in particular the CB2 receptor, may serve for the development of a neuroprotective therapy in TDP-43-related disorders. We are presently engaged in pharmacological experiments to investigate this possibility.

http://link.springer.com/10.1007/s11481-015-9602-4

Source: Journal of NeuroImmune Pharmacology - March 29, 2015 Category: Drugs & Pharmacology Source Type: research