Is Bevacizumab Truly a New Standard in Cervical Cancer?Is Bevacizumab Truly a New Standard in Cervical Cancer?

New data on quality of life show 'convincingly' that it is not adversely affected, but does it all add up to a new standard? Medscape Medical News
Source: Medscape Hematology-Oncology Headlines - Category: Cancer & Oncology Tags: Hematology-Oncology News Source Type: news

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In this study, two new N, N–disubstituted thiocarbamide compounds 1 and 2 have been synthesized and characterized by different spectroscopic (FT-IR, 1H and 13C NMR, UV–Visible) techniques. The molecular structure of both compounds was determined by single crystal X-ray diffraction and Hirshfeld surfaces analysis. Compounds 1 and 2 were also screened for their in vitro cytotoxicity, DNA damage and cell cycle arrest studies.
Source: Journal of Molecular Structure - Category: Molecular Biology Source Type: research
Publication date: Available online 17 March 2019Source: Journal of Molecular StructureAuthor(s): G. Sasikumar, S. Arulmozhi, A. Ashma, A. Sudha, S.J. Askar aliAbstractThis research work was emphasized about synthesis of mixed ligands of Co(II), Ni(II), Cu(II) and Zn(II) complexes of the type [M(L)(phen)] 1–4 and [M(L)(bpy)] 5–8 where, L = potassium (S, E)-2-((5-bromo-2-hydroxybenzylidene)amino)propanoate (derived from 5-bromosalicylaldehyde and l-alanine), phen = 1, 10 phenanthroline and bpy = 2, 2′-bipyridyl. Both phen and bpy act as an auxiliary ligand. The synthesized metal(II) complexes ch...
Source: Journal of Molecular Structure - Category: Molecular Biology Source Type: research
Publication date: Available online 16 March 2019Source: Pesticide Biochemistry and PhysiologyAuthor(s): Darpan Raghav, Susobhan Mahanty, Krishnan RathinasamyAbstractKaranjin, a furanoflavonol from Pongamia pinnata L is used in agricultural practices for its pesticidal, insecticidal and acaricidal activities. It is commercially available as a bio-pesticide targeting a wide variety of pests. The present study was intended to evaluate the biochemical interactions of karanjin with bovine serum albumin (BSA) and study its toxicological effects on mammalian and bacterial cell lines. Karanjin bound to BSA at a single site with a ...
Source: Pesticide Biochemistry and Physiology - Category: Biochemistry Source Type: research
This study investigated treatment outcomes and prognostic factors of survival in CEC patients undergoing definitive radiotherapy or concurrent chemoradiotherapy (CCRT). Ninety-one CEC patients were treated by intensity-modulated radiation therapy (IMRT) and three-dimensional conformal radiation therapy (3DCRT) between July 2007 and September 2017. The mean prescription dose was 64 Gy (range 54-70 Gy) delivered as 1.8-2.2 Gy per fraction per day, 5 days a week. Out of 91 patients, 34 received concurrent cisplatin-based chemotherapy (CT) including 18 patients who also received neoadjuvant CT. Overall survival (OS), locoregio...
Source: Bosnian Journal of Basic Medical Sciences - Category: General Medicine Tags: Bosn J Basic Med Sci Source Type: research
ConclusionsOur study suggests that in terms of oncological outcome FIGO IIB cervical cancer patients benefit from a combination of surgery and radiochemotherapy. However, in the presence of lymph node infestation, surgery does not add substantial benefit to the patient.
Source: Journal of Cancer Research and Clinical Oncology - Category: Cancer & Oncology Source Type: research
Surge in number of smear tests come as laboratories prepare for shake-up Related items fromOnMedica Preventing cervical cancer: how a screening switch and HPV vaccination should cut cancer rates Social media could help raise breast screening take-up Armed forces wives at greater risk of perinatal depression Cervical screening intervals should be extended Breast cancer age profile younger in non-white women
Source: OnMedica Latest News - Category: UK Health Source Type: news
AbstractCervical cancer continues to be a global health problem; despite the potential for prevention through organised screening programmes that can detect and treat pre-cancerous lesions and also more recently, the availability of HPV (Human Papilloma Virus) vaccines. While routine screening with Pap smear testing has reduced the burden of cervical cancer in the high-income countries, the implementation of organised Pap-based screening programmes has not been found feasible in low-resource settings due to a lack of health care delivery infrastructure and limited health budgets. The well-established causal relationship be...
Source: Indian Journal of Surgical Oncology - Category: Cancer & Oncology Source Type: research
Conclusions: We concluded that HPV prevalence and genotype distribution in women with or without clinical findings is an important predictor of cervical cancer.
Source: Indian Journal of Medical Microbiology - Category: Microbiology Authors: Source Type: research
Public health campaign triggers surge in numbers attending cervical screenings at ‘worst possible time’Women could be forced to wait months for cervical cancer screening results because the planned closure of dozens of laboratories has left the service in “meltdown”, the Guardian has been told.The crisis has been triggered by a surge in numbers of women attending smear tests following a governmentpublic awareness campaign launched earlier this month. The campaign coincides with an exodus of biomedical scientists due to a restructuring process that will reduce nearly 50 hospital screening laboratorie...
Source: Guardian Unlimited Science - Category: Science Authors: Tags: NHS Health Cervical cancer Health policy Public services policy Science Society Politics UK news Source Type: news
(MedPage Today) -- Black race, higher-stage disease tied to lower likelihood of receiving boost
Source: MedPage Today Hematology/Oncology - Category: Hematology Source Type: news
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