[Techniques for quantification of liver fat in risk stratification of diabetics].

[Techniques for quantification of liver fat in risk stratification of diabetics].
Radiologe. 2015 Mar 25;
Authors: Kühn JP, Spoerl MC, Mahlke C, Hegenscheid K
Abstract
CLINICAL/METHODICAL ISSUE: Fatty liver disease plays an important role in the development of type 2 diabetes. Accurate techniques for detection and quantification of liver fat are essential for clinical diagnostics.
STANDARD RADIOLOGICAL METHODS: Chemical shift-encoded magnetic resonance imaging (MRI) is a simple approach to quantify liver fat content.
METHODICAL INNOVATIONS: Liver fat quantification using chemical shift-encoded MRI is influenced by several bias factors, such as T2* decay, T1 recovery and the multispectral complexity of fat.
PERFORMANCE: The confounder corrected proton density fat fraction is a simple approach to quantify liver fat with comparable results independent of the software and hardware used.
ACHIEVEMENTS: The proton density fat fraction is an accurate biomarker for assessment of liver fat.
PRACTICAL RECOMMENDATIONS: An accurate and reproducible quantification of liver fat using chemical shift-encoded MRI requires a calculation of the proton density fat fraction.
PMID: 25802035 [PubMed - as supplied by publisher]

Source: Der Radiologe - March 25, 2015 Category: Radiology Authors: Kühn JP, Spoerl MC, Mahlke C, Hegenscheid K Tags: Radiologe Source Type: research