Do diet drinks really make you fatter?

Conclusion This large US-representative cross-sectional study indicates that overweight and obese people drink more diet drinks than healthy-weight people, but still consume the same amount of calories as those drinking sugar-sweetened drinks. The extra calories were made up by eating more food. This suggests that people who are overweight or obese may be switching to diet drinks to reduce their calorie intake when trying to control or reduce their weight. However, they consumed significantly more calories from food, which brought their total energy intake in line with those drinking sugar-sweetened drinks – effectively cancelling out any calorie reducing effect of the diet drink. The researchers noted that this may mean that, "When adults replace SSBs with non-calorie beverage alternatives, they make few other changes to their diet." The study had a number of strengths, including its large sample size and the fact that it was broadly representative of the US population, which has some similarities to the UK. However, there were some limitations that should be considered: The diet information used in the research relied on participants accurately and honestly recalling their food and drink intake in the previous 24-hour period. If any of the weight groups systematically under- or overestimated their food and drink intake, this would distort the results. The study was conducted in the US. The drinking habits of people in the UK may differ, which c...
Source: NHS News Feed - Category: Consumer Health News Tags: Food/diet Neurology Obesity Source Type: news

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Conclusion The periconceptional environment and lifestyle factors modify sperm epigenome. This alteration might be maintained in the zygote and throughout development, thereby leading to the inheritance of newly acquired pathologies. The role of sperm miRNA, not only as innovative markers of fertility issues but also as vectors involved in the inheritance of paternal diseases, appears to be crucial. Overweight and obesity seem to alter sperm miRNA profile, thereby leading to transmission of different miRNA profiles in zygote, with consequences on embryo development. In long term, metabolic disorders have been described in...
Source: Frontiers in Genetics - Category: Genetics & Stem Cells Source Type: research
Katherine Samaras1,2,3*, Henrik Tevaerai4, Michel Goldman5, Johannes le Coutre6,7 and Jeff M. P. Holly8 1Department of Endocrinology, St Vincent's Hospital, Darlinghurst, NSW, Australia 2Diabetes and Metabolism, Garvan Institute of Medical Research, Darlinghurst, NSW, Australia 3St Vincent's Hospital, St Vincent's Clinical School, Darlinghurst, NSW, Australia 4Bern University Hospital, Bern, Switzerland 5Institute for Interdisciplinary Innovation in Healthcare, Universite Libre de Bruxelles, Bruxelles, Belgium 6Department of Medicine, Imperial College London, London, United Kingdom 7Nes...
Source: Frontiers in Endocrinology - Category: Endocrinology Source Type: research
Conclusion The expression of the components of the PTN-MK-RPTPβ/ζ axis in immune cells and in inflammatory diseases suggests important roles for this axis in inflammation. Pleiotrophin has been recently identified as a limiting factor of metainflammation, a chronic pathological state that contributes to neuroinflammation and neurodegeneration. Pleiotrophin also seems to potentiate acute neuroinflammation independently of the inflammatory stimulus while MK seems to play different -even opposite- roles in acute neuroinflammation depending on the stimulus. Which are the functions of MK and PTN in chronic neuroinfla...
Source: Frontiers in Pharmacology - Category: Drugs & Pharmacology Source Type: research
In this study, we explore shared epigenetic mechanisms of the association between mtDNA content and insulin levels, supporting the developmental origins of this link. First, the association between cord blood insulin and mtDNA content in 882 newborns of the ENVIRONAGE birth cohort was assessed. Cord blood mtDNA content was established via qPCR, while cord blood levels of insulin were determined using electrochemiluminescence immunoassays. Then the cord blood DNA methylome and transcriptome were determined in 179 newborns, using the human 450K methylation Illumina and Agilent Whole Human Genome 8 × 60 K microarrays, r...
Source: Frontiers in Genetics - Category: Genetics & Stem Cells Source Type: research
Conclusion Women of Hawaiian and Pacific Islander descent demonstrate a similar yet unique constellation of risk and protective factors for preterm birth as compared with other groups at high risk for preterm birth. Interventions aimed to prevent preterm birth need to support the specific needs of this population. [...] Thieme Medical Publishers 333 Seventh Avenue, New York, NY 10001, USA.Article in Thieme eJournals: Table of contents  |  Abstract  |  Full text
Source: American Journal of Perinatology - Category: Perinatology & Neonatology Authors: Tags: Original Article Source Type: research
DiscussionIf effective, the Baby Steps programme could be translated into a primary care-based intervention that women with GDM are referred to in the postnatal period. This could help them make lifestyle changes that could reduce their future risk of T2D.Trial registrationISRCTN,ISRCTN17299860. Registered on 5 April 2017.
Source: Trials - Category: Research Source Type: clinical trials
Discussion Intrauterine growth retardation or fetal growth retardation is due to a pathological process that causes decelerated fetal growth velocity. Small-for-gestational age (SGA) is an infant with growth parameters below the normal range for gestational age. More commonly, SGA is defined as a birth weight
Source: PediatricEducation.org - Category: Pediatrics Authors: Tags: Uncategorized Source Type: news
TUESDAY, Nov. 13, 2018 -- Kids who were born large and whose mothers developed a form of diabetes during pregnancy have nearly triple the odds of becoming overweight or obese in childhood, new research shows. " Just like smoking, alcohol consumption...
Source: Drugs.com - Daily MedNews - Category: General Medicine Source Type: news
Conclusion The results obtained from this research shows, in general, the fragility in the social and political infrastructure necessary to improve the living conditions of populations, particularly those that depend on family agriculture in drought prone areas. The conditions of social, economic and environmental vulnerabilities presented in the region can be amplified by the drought process, and can aggravate the impacts resulting drought events, thus disadvantaging the population of this region, as shown in the Fig. 1. The general perception of the interviewees of the health sector shows an agreement with what is found...
Source: PLOS Currents Disasters - Category: International Medicine & Public Health Authors: Source Type: research
CONCLUSION: In this study, Mexican-Americans in the US had more risk factors for CLD than their counterparts in Mexico. These findings can be used to design and implement more effective health promotion policies and programs to address the specific factors that put Mexicans at higher risk of developing CLD in both countries. PMID: 30310261 [PubMed - in process]
Source: World Journal of Gastroenterology : WJG - Category: Gastroenterology Authors: Tags: World J Gastroenterol Source Type: research
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