ERAP1 is a critical regulator of inflammasome-mediated proinflammatory and ER stress responses

In addition to its role in antigen presentation, recent reports establish a new role for endoplasmic reticulum aminopeptidase 1 (ERAP1) in innate immunity; however, the mechanisms underlying these functions ar...

Source: BMC Immunology - March 4, 2022 Category: Allergy & Immunology Authors: Maja K. Blake, Patrick O ’Connell, Yuliya Pepelyayeva, Sarah Godbehere, Yasser A. Aldhamen and Andrea Amalfitano Tags: Research Source Type: research