Characterization and initial demonstration of < em > in  vivo < /em > efficacy of a novel heat-activated metalloenediyne anti-cancer agent

CONCLUSION: By leveraging the unique thermal activation properties of metalloenediynes, we propose that localized moderate hyperthermia can be used to confine the cytotoxicity of these compounds to tumors, while sparing normal tissue.PMID:35236209 | DOI:10.1080/02656736.2021.2024280
Source: International Journal of Hyperthermia - Category: Internal Medicine Authors: Source Type: research