Coupling of ascorbate and nitric oxide dynamics in vivo in the rat hippocampus upon glutamatergic neuronal stimulation: a novel functional interplay.

CONCLUSIONS: The coupling between NO and ascorbate upon glutamatergic activation points to a functional impact on the activities of both compounds and, although the precise molecular mechanism needs to be clarified, such a coupling lays the foundations for new regulatory mechanisms in the brain.
PMID: 25783673 [PubMed - as supplied by publisher]

Source: Brain Research Bulletin - March 14, 2015 Category: Neurology Authors: Ferreira NR, Lourenço C, Barbosa RM, Laranjinha J Tags: Brain Res Bull Source Type: research