Entomological outcomes of cluster-randomised, community-driven dengue vector-suppression interventions in Kampong Cham province, Cambodia

by Jacob Bigio, Leo Braack, Thy Chea, Srun Set, Sokha Suon, Pierre Echaubard, John Hustedt, Mark Debackere, Bernadette Ramirez, Didot Budi Prasetyo, Sam Bunleng, Alexandra Wharton-Smith, Jeffrey Hii Cambodia has one of the highest dengue infection rates in Southeast Asia. Here we report quantitative entomological results of a large-scale cluster-randomised trial assessing the impact on vector populations of a package of vector control interventions including larvivorous guppy fish in househol d water containers, mosquito trapping with gravid-ovitraps, solid waste management, breeding-container coverage through community education and engagement for behavioural change, particularly through the participation of school children. These activities resulted in major reductions in Container Ind ex, House Index, Breteau Index, Pupal Index and Adult Index (all p-values 0.002 or lower) in the Intervention Arm compared with the Control Arm in a series of household surveys conducted over a follow-up period of more than one year, although the project was not able to measure the longer-term susta inability of the interventions. Despite comparative reductions in Adult Index between the study arms, the Adult Index was higher in the Intervention Arm in the final household survey than in the first household survey. This package of biophysical and community engagement interventions was highly eff ective in reducing entomological indices for dengue compared with the control group, but caution i...
Source: PLoS Neglected Tropical Diseases - Category: Tropical Medicine Authors: Source Type: research