I ’m leading a long Covid trial – it’s clear Britain has underestimated its impact | Amitava Banerjee

Scientists and politicians have focused on the short-term impact of the virus – but we can no longer leave chronic patients to struggleDespite apprehension about high Covid-19 rates, my family Christmas in Yorkshire was wonderful. Unfortunately, the week after was marred by headache, fever and malaise. And a PCR test confirmed the worst – I had Covid-19 for the second time. My second encounter has been dominated by severe fatigue and reduced concentration, which though improving, have not yet resolved more than two weeks later. Worryingly, what I know aboutlong Covid suggests that this could persist for several months – or longer.The World Health Organizationdefines long Covid as ongoing symptoms “three months from the onset of Covid-19”. In December, theOffice for National Statistics (ONS) estimated that more than 1.3 million people in the UK had symptoms for four weeks or more after Covid-19, of whom 892,000 people (70%) had symptoms that persisted for at least 12 weeks, and 506,000 (40%) for at least one year. Dr Melissa Heightman, who leads theUniversity College London hospital specialist long Covid clinic says that breathlessness, fatigue, cough, myalgia, chest pain, headache, “brain fog” and palpitations are most commonly reported. Butmany other symptoms may be present.Amitava Banerjee is professor of clinical data science and honorary consultant cardiologist at University College London and is leading the Stimulate-ICP study to...
Source: Guardian Unlimited Science - Category: Science Authors: Tags: Long Covid Coronavirus UK news Health Science Source Type: news

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Nutr Res Rev. 2021 Oct 20:1-42. doi: 10.1017/S0954422421000317. Online ahead of print.ABSTRACTScientists are working to identify prevention/treatment methods and clinical outcomes of Coronavirus Disease 2019 (COVID-19). Nutritional status and diet have a major impact on the COVID-19 health-disease process, mainly due to the bidirectional interaction between gut-lung axis. Individuals with inadequate nutritional status have a pre-existing imbalance in the gut microbiota and immunity as seen in obesity, diabetes, hypertension, or other chronic diseases. Communication between the gut microbiota and lungs or other organs and s...
Source: Cell Research - Category: Cytology Authors: Source Type: research
Most patients with coronavirus disease 2019 (COVID-19) have mild to moderate illness not requiring hospitalization. However, no study has detailed the evolution of symptoms in the first month of illness. At our institution, we conducted remote (telephone and video) visits for all adult outpatients diagnosed with COVID-19 within 24 h of a positive nasopharyngeal polymerase chain test for SARS-CoV-2. We repeated regular video visits at 7, 14, and 28 days after the positive test, retrospectively reviewed the prospective data collected in the remote visits, and constructed a week by week profile of clinical illness, throu...
Source: Medicine - Category: Internal Medicine Tags: Research Article: Observational Study Source Type: research
Conclusion During the first peak of SARS-CoV-2, the number of patients reporting COVID-19 symptoms appeared high and was associated with high levels of anxiety. As only a small number have been swab-tested, this may suggest that larger numbers of untested individuals have had COVID-19 with mild symptoms. Fe atures of inflammatory rheumatic illnesses may mimic COVID-19 symptoms and create diagnostic difficulty (joint pain and fatigue) whilst anxiety may lead to over-reporting of symptoms in the absence of infection. The key symptoms of fever, cough and SOB were less common and may be most reliable.Disclosure M. Lw...
Source: Rheumatology - Category: Rheumatology Source Type: research
AbstractObjectivesThese 2 parallel studies (K031 and K032) aim to evaluate the safety of KB109 in addition to supportive self-care (SSC) compared with SSC alone in outpatients with mild to moderate coronavirus disease 2019 (COVID-19). KB109 is a novel synthetic glycan that was formulated to modulate the gut microbiome composition and metabolic output in order to increase beneficial short-chain fatty acid (SCFA) production in the gut. The K031 study is designed to evaluate the safety of KB109 and characterize its impact on the natural progression of COVID-19 in patients with mild to moderate disease. The K032 study is evalu...
Source: Trials - Category: Research Source Type: clinical trials
Arh Hig Rada Toksikol. 2021 Mar 30;72(1):36-41. doi: 10.2478/aiht-2021-72-3530. Print 2021 Mar 1.ABSTRACTHealthcare workers (HCWs) are considered to run a higher occupational risk of becoming infected with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), and develop coronavirus disease (COVID-19) than the rest of the population. The aim of this study was to describe and analyse the characteristics of work-related COVID-19 in Croatian HCWs. Study participants were HCWs who contacted their occupational physician between 1 May 2020 and 12 November 2020 with a request for the registration of COVID-19 as an occupat...
Source: Arhiv za Higijenu Rada i Toksikologiju - Category: Occupational Health Authors: Source Type: research
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