A Cohort-Based Case Report: The Impact of Ketamine-Assisted Therapy Embedded in a Community of Practice Framework for Healthcare Providers With PTSD and Depression

Amid an international pandemic and a worsening mental health crisis, ketamine-assisted therapy is emerging as a promising solution for those deemed “treatment resistant.” Post-traumatic stress disorder (PTSD) and depression are on the rise, with accelerating direct (e.g., burden of suffering) and indirect (e.g., disability/role impairment and impact on family) costs. Psychedelic-assisted therapies show significant promise in the treatment of a number of clinically challenging conditions, including depression, anxiety, PTSD, addiction, and end-of-life distress. Ketamine is currently the only safe, effective and legal widely available psychedelic-like medicine. To address the echo pandemic of health care provider distress, a multi-disciplinary team was charged with developing a ketamine-assisted psychotherapy program, delivered in a community of practice (CoP) group model and evaluated in a quality improvement framework. Program evaluation occurred through mixed methods. Quantitative mental health assessments included the PHQ-9 for depression, the PCL-5 for PTSD, GAD-7 for generalized anxiety disorder (GAD), and B-IPF for work/life functionality. Participant narrative feedback was collected to evaluate outcomes and for quality improvement purposes. Mean mental health scores were collected across three cohorts, totaling 94 patients. The mean aggregate scores of participants meeting the mental health assessment cut-off criteria (screening positive) were analyzed to as...
Source: Frontiers in Psychiatry - Category: Psychiatry Source Type: research

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ConclusionA growing body of literature has shown an association between SARS ‐CoV‐2 infection and the development of different types of CNS demyelination. Although causality cannot readily be inferred, this review may suggest a probable causal relationship, through a para-infectious or post-infectious immune-mediated etiology in COVID-19 patients. This relationship needs to be clarified in future research.
Source: Journal of Neurology - Category: Neurology Source Type: research
ConclusionsImprovement was seen in most patients. One year after the start of treatment, more than half of the patients were untreated and around one-third in remission. Residual symptoms and deficits were common regardless of treatment.
Source: Journal of Neurology - Category: Neurology Source Type: research
ConclusionAn AMT assembled during the COVID-19 pandemic showed high competency and effectiveness, and had favourable impact on the main responsible physicians who activated the team.
Source: Canadian Journal of Anesthesia - Category: Anesthesiology Source Type: research
ConclusionsGiven the perceived benefits of regional over general anesthesia, approximately half of the members of three regional anesthesia societies seem to have expanded their use of regional anesthesia techniques during the initial surge of the COVID-19 pandemic.
Source: Canadian Journal of Anesthesia - Category: Anesthesiology Source Type: research
AbstractSynaptic plasticity, the substrate for learning, has been established in neural reward circuits and might involve in the learning of addictive behaviors. Long-term exposure to addictive drugs caused long-lasting memories of the drug experience. The main clinical problem that involves the persistence of addiction is a relapse that is resulted from the exposure to cues of the drug experience. Persistent forms of synaptic plasticity are associated with some of the behavioral effects of addictive drugs. Here, we present the underlying mechanisms of plasticity induced by different brain reward circuitry. Therefore, we f...
Source: Neurological Sciences - Category: Neurology Source Type: research
This study is a retrospective database review of all telestroke requests at one academic vascular neurology center telestroke network with seven remote sites in the USA between March 15 and April 30, 2020. Data were compared with historical cohort spanning same time frame in 2019 using parametric or nonparametric methods as appropriate. Among telestroke requests, characteristics of age, gender, race/ethnicity, National Institutes of Health Stroke Scale (NIHSS), primary diagnosis of AIS or transient ischemic attack (TIA), and number of patients receiving intravenous alteplase (IV-rtPA) and endovascular therapy (ET) were rec...
Source: Neurological Sciences - Category: Neurology Source Type: research
ConclusionaVNS ameliorates gastric motility and improves the mental state in the FD-like rat, probably via inhibiting the CRF pathway.
Source: Digestive Diseases and Sciences - Category: Gastroenterology Source Type: research
FRIDAY, Jan. 21, 2022 -- There was increased use of telemedicine for surgical consults among some historically underrepresented patient groups during the second phase of the pandemic, according to a study published in the February issue of the...
Source: Drugs.com - Pharma News - Category: Pharmaceuticals Source Type: news
The number of outpatient visits for mental health and substance use by physicians jumped 27% in the first year of the COVID-19 pandemic, astudy published today inJAMA Network Open has found.“We observed increases in mental health and substance use visits during the COVID-19 pandemic that, consistent with surveys finding high levels of self-reported anxiety, depression, and stress in physicians during the pandemic, may indicate worsening physician mental health,” wrote Daniel T. Myr an, M.D., M.P.H., of the Ottawa Hospital Research Institute in Canada and colleagues.The researchers analyzed data from the records...
Source: Psychiatr News - Category: Psychiatry Tags: COVID-19 in-person visits JAMA Network Open mental health pandemic physicians psychiatrists substance use virtual visits Source Type: research
Paramount Pictures and Skydance said the seventh and eighth installments in the Mission Impossible franchise would be delayed due to the ongoing pandemic. #paramountpictures #missionimpossible7 #tomcruise #installments
Source: Reuters: Health - Category: Consumer Health News Source Type: news
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