Olfactory reference plus Truman symptoms in one patient with Gilbert syndrome and antiphospholipid antibodies (Hughes disease) secondary to probable chronic Lyme neuroborreliosis

Psychol Med. 2022 Jan 11:1-2. doi: 10.1017/S0033291721005481. Online ahead of print.ABSTRACTAfter reading an article in the journal, regarding affective disorders in patients with rare illnesses, the authors would like to discuss a case of non-affective psychosis, presenting with olfactory reference and Truman symptoms, in a patient with three unusual conditions: Gilbert disease, Hughes syndrome and Lyme neuroborreliosis.PMID:35012695 | DOI:10.1017/S0033291721005481
Source: Psychological Medicine - Category: Psychiatry Authors: Source Type: research

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Conclusion: This systematic review, including all reported cases and our case report, supports evidence of ocular infection ofBorrelia species. Furthermore, in case of suspicion of infection and seronegativity, it is justified to look forBorrelia in eye tissue samples. In addition, microscopy without using PCR is not sufficient to confirm the diagnosis of borreliosis on ocular tissue. In the articles studied, there was no unambiguous recommendation of treatment.Ophthalmic Res
Source: Ophthalmic Research - Category: Opthalmology Source Type: research
Intern Med. 2022 Jan 13. doi: 10.2169/internalmedicine.8784-21. Online ahead of print.ABSTRACTAnkylosing spondylitis (AS) is rarely accompanied by other autoimmune diseases and/or hematologic disorders. We herein report a 46-year-old man with AS coexisting with relapsing polychondritis (RP), antiphospholipid syndrome (APS) and myelodysplastic syndrome (MDS). While receiving anti-TNF therapy for AS, the patient developed anemia and was diagnosed with MDS. After six months, he developed swelling and redness of the nose and both auricles. RP was diagnosed by an ear biopsy. Afterward, during the evaluation of a repeated fever,...
Source: Internal Medicine - Category: Internal Medicine Authors: Source Type: research
Semin Thromb Hemost DOI: 10.1055/s-0041-1742083Thrombotic antiphospholipid syndrome (APS) is a condition in which thrombosis in venous, arterial, and/or small vessels is ascribed to the presence of antiphospholipid antibodies (aPL). Among the various proposed pathogenic theories to explain thrombotic APS, those involving the interaction between aPL and the protein C system have gained much consensus. Indeed, robust data show an acquired activated protein C resistance (APC-R) in these patients. The role of aPL in this impairment is clear, but the mechanism of action is uncertain, as the type of aPL and to what extent aPL ar...
Source: Seminars in Thrombosis and Hemostasis - Category: Hematology Authors: Tags: Review Article Source Type: research
Psychol Med. 2022 Jan 11:1-2. doi: 10.1017/S0033291721005481. Online ahead of print.ABSTRACTAfter reading an article in the journal, regarding affective disorders in patients with rare illnesses, the authors would like to discuss a case of non-affective psychosis, presenting with olfactory reference and Truman symptoms, in a patient with three unusual conditions: Gilbert disease, Hughes syndrome and Lyme neuroborreliosis.PMID:35012695 | DOI:10.1017/S0033291721005481
Source: Psychological Medicine - Category: Psychiatry Authors: Source Type: research
CONCLUSIONS AND RELEVANCE: Among patients younger than 21 years of age with provoked venous thromboembolism, anticoagulant therapy for 6 weeks compared with 3 months met noninferiority criteria based on the trade-off between recurrent venous thromboembolism risk and bleeding risk.TRIAL REGISTRATION: ClinicalTrials.gov Identifier: NCT00687882.PMID:35015038 | DOI:10.1001/jama.2021.23182
Source: Atherosclerosis - Category: Cardiology Authors: Source Type: research
CONCLUSIONS AND RELEVANCE: Approximately 1 in 5 adults in the US had an STI in 2018. Rates of gonorrhea, chlamydia, and syphilis in the US have increased, while rates of HSV-1 and HSV-2 have declined. Ceftriaxone, doxycycline, penicillin, moxifloxacin, and the nitroimidazoles are effective treatments for gonorrhea, chlamydia, syphilis, Mycoplasma genitalium, and trichomoniasis, respectively, but antimicrobial resistance limits oral therapies for gonorrhea and Mycoplasma genitalium, and no cure is available for genital herpes.PMID:35015033 | DOI:10.1001/jama.2021.23487
Source: Herpes - Category: Infectious Diseases Authors: Source Type: research
We present a case of a patient working in Africa, who returned with fever, constitutional symptoms, headache, and blurred vision. An initial diagnosis of malaria was made, and additional workup revealed Borrelia burgdorferi co‐infection and antiphospholipid syndrome. The differential diagnosis of fever in a returned traveler is wide and challenging. We present a case of a patient working in Africa, who returned with fever, constitutional symptoms, headache, and blurred vision. An initial diagnosis of malaria was made, and additional workup revealed Borrelia burgdorferi co‐infection and antiphospholipid syndrome.
Source: Clinical Case Reports - Category: Journals (General) Authors: Tags: Case Report Source Type: research
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