Knowledge check in Brugada syndrome : A rapid fire session

A 5-minute session: Answers are my own. Please cross-check. 1. Is Brugada syndrome clinical or ECG diagnosis? Always clinical. Never get confused on this. 2. Spontaneous type 1 vs Induced Type 1 (from type 2) which carries more risk? Both are risky since they are close cousins. But, spontaneous type 1 is the dreaded devil.  3. Is Brugada primarily a defect of myocardial depolarization or repolarisation? Not clear. Often in both. In fact a mismatch between them. (Don’t ask how Na+ Channel defect affects repolarisation !) 4. Is Brugada VT is monomorphic, polymorphic? Both. What determines morphology is not clear though. (All de-nova monomorphic VT will degenerate to polymorphic en route to cardiac arrest) 5. Should  Fever induced Brugada pattern be investigated further? Better, it is not to be reported in ECG. May not be important in the majority if there is no adverse family history. (If the patient is well educated and afflicted  by Dr.Google and cardiologists can’t escape from ordering sophisticated tests)      6. What is the overlap between ERS and Brugada? It is all about the Idiosyncrasy of the K+ channel phenotypes ( Transmural dispersion heterogeneity )   7. Is a benign Brugada better than a malignant ERS? Yes, it would seem so. (Inferior or Infero -lateral ERS prone for primary VF in case they develop ischemic / ? also non-ischemic stress) 8. How important is the link between Brugada and L...
Source: Dr.S.Venkatesan MD - Category: Cardiology Authors: Tags: cardiac electrophysiology cardiology -Therapeutics Cardiology -unresolved questions Cardiology-Arrhythmias early repolarisation syndrome Electro physiology Electrocardiography-ECG ICD and Pacemakers amiodarone for brugada brugada syndrom Source Type: blogs