Novel lipidomic signature associated with metabolic risk in women with and without polycystic ovary syndrome

CONCLUSIONS: Our data indicate that a distinct lipidomic signature comprising high LPI(18:0) and low DHA-containing lipids are associated with key metabolic risk factors that cluster in PCOS, independent of PCOS status. Prospective studies are needed to corroborate these findings in larger cohorts of women with varying PCOS phenotypes.PMID:34971378 | DOI:10.1210/clinem/dgab931

Source: The Journal of Clinical Endocrinology and Metabolism - December 31, 2021 Category: Endocrinology Authors: Aya Mousa Kevin Huynh Stacey J Ellery Boyd J Strauss Anju E Joham Barbora de Courten Peter J Meikle Helena J Teede Source Type: research