Antifouling Diterpenoids from the Sponge Dendrilla antarctica

Chem Biodivers. 2021 Dec 29:e202100618. doi: 10.1002/cbdv.202100618. Online ahead of print.ABSTRACTTwo nor-diterpenes, 9,11-dihydrogracilin A (1) and the previously unreported 9,11-dihydrogracillinone A (2), were isolated from the sponge Dendrilla antarctica. The sponge was collected by trawling at a depth of 49 m, from the research vessel Puerto Deseado, near the coast of Tierra del Fuego, farther north than the reported habitat for this species. Since these compounds were particularly abundant and the sponge was free from epibionts, both 1 and 2 were included in soluble-matrix paints and tested for antifouling activity in the ocean. The results obtained from these experiments clearly indicated a potent antifouling activity for both compounds against a variety of colonizing organisms, and established a probable role as natural antifoulants for these abundant secondary metabolites and other structurally related compounds previously isolated from Dendrilla spp.PMID:34964245 | DOI:10.1002/cbdv.202100618

Source: Chemistry and Biodiversity - December 29, 2021 Category: Biochemistry Authors: Iv án M Prieto Anal ía Paola Miriam P érez M ónica García Guillermo Blustein Laura Schejter Jorge A Palermo Source Type: research