What Evaluation Should Be Considered for Heavy Menstrual Bleeding?

Discussion Heavy menstrual bleeding is a common problem. The rates depend on the population and underlying cause, but can occur 30% of adolescent females who go to a gynecologist. Average menstrual blood loss is 30-40 ml. Hypermenorrhea or menorrhagia are regular menstrual cycles that last too long (>7 days) or are too heavy (> 80 ml blood loss). Metrorrhagia is irregular menstrual bleeding. Menometrorrhagia is abnormally heavy bleeding that occurs with an irregular timing. Dysfunctional uterine bleeding is a more generic term describing prolonged, excessive or frequent, unpatterned uterine bleeding that is not related to an anatomical uterine abnormality or systemic cause. Adolescents can have a very difficult time accurately describing their menses but abnormal bleeding is considered pathologic if “…menstrual loss requiring pad or tampon changes every 1-2 h, with anything longer resulting in ‘flooding’ or ‘accidents’….” Problems associated with heavy menstrual bleeding include anemia, fatigue, missed school and difficulties participating in social and sporting activities. For young women with various disabilities it may offer the additional challenge of difficulty with managing menstrual hygiene. Causes of heavy menstrual bleeding include: Anovulation – most common cause and is normal in the first 2-3 years after menarche due to the immature hypothalamic-pituitary-ovarian axis Pregnancy and pregnancy related co...
Source: PediatricEducation.org - Category: Pediatrics Authors: Tags: Uncategorized Source Type: news

Related Links:

Conclusions: Mechanical ventilation leads to down-regulation of R-spondin1. R-spondin1 may enhance the interaction of leucine-rich repeat containing G-protein coupled receptor 5 and apoptosis-stimulating protein of p53 2, thus inactivating p53-mediated proapoptotic pathway in cyclic stretched mouse lung vascular endothelial cells. R-spondin1 may have clinical benefit in alleviating mechanical ventilator-induced lung injury.
Source: Critical Care Medicine - Category: Emergency Medicine Tags: Online Laboratory Investigation Source Type: research
Conclusions: The use of real-time ultrasound guidance was associated with a lower rate of iatrogenic pneumothoraces.
Source: Critical Care Medicine - Category: Emergency Medicine Tags: Clinical Investigations Source Type: research
Objectives: To determine if higher fresh frozen plasma and platelet to packed RBC ratios are associated with lower 24-hour mortality in bleeding pediatric trauma patients. Design: Retrospective cohort study using the Pediatric Trauma Quality Improvement Program Database from 2014 to 2016. Setting: Level I and II pediatric trauma centers participating in the Trauma Quality Improvement Program Patients: Injured children (≤ 14 yr old) who received massive transfusion (≥ 40 mL/kg total blood products in 24 hr). Of 123,836 patients, 590 underwent massive transfusion, of which 583 met inclusion cri...
Source: Critical Care Medicine - Category: Emergency Medicine Tags: Pediatric Critical Care Source Type: research
This study utilized data from The National Longitudinal Transition Study-2 (NLTS-2), a 10-year longitudinal dataset that includes high school students with various disabilities. The study proposed a theoretical framework for sense of school community through maximized school assets and minimized school challenges. The study sample included a total of 1,180 high school students, 11th (n = 443) and 12th (n = 737) graders who completed surveys. Multiple linear regression analysis revealed that a combination of school assets and school challenges of high school experience predicted sense of school c...
Source: Journal of Prevention and Intervention in the Community - Category: International Medicine & Public Health Tags: J Prev Interv Community Source Type: research
Conclusion: The process of establishing and undertaking community groups in itself appeared to have a positive perceived impact on the community. However, sustained behaviour change, power dynamics and financial incentives need to be carefully considered during implementation and sustaining the community groups. PMID: 31190635 [PubMed - in process]
Source: Global Health Action - Category: International Medicine & Public Health Tags: Glob Health Action Source Type: research
Source: Journal of Biomedical Nanotechnology - Category: Nanotechnology Authors: Tags: Articles Source Type: research
Source: Journal of Biomedical Nanotechnology - Category: Nanotechnology Authors: Tags: Articles Source Type: research
Source: Journal of Biomedical Nanotechnology - Category: Nanotechnology Authors: Tags: Articles Source Type: research
Publication date: Available online 13 June 2019Source: CellAuthor(s): Chien-Hsiang Hsu, Steven J. Altschuler, Lani F. WuSummaryChemotherapy is designed to induce cell death. However, at non-lethal doses, cancer cells can choose to remain proliferative or become senescent. The slow development of senescence makes studying this decision challenging. Here, by analyzing single-cell p21 dynamics before, during, and days after drug treatment, we link three distinct patterns of early p21 dynamics to final cell fate. Surprisingly, while high p21 expression is classically associated with senescence, we find the opposite at early ti...
Source: Cell - Category: Cytology Source Type: research
This study could be beneficial for: (i) Clinicians to receive second opinion from the CAD system for early diagnosis, and (ii) Researchers to analyze and enhance the existing state-of-art techniques used in CAD system, which may further reduce the gap of variability between intra and inter observer.Graphical abstract
Source: IRBM - Category: Biomedical Engineering Source Type: research
More News: Accidents | Anemia | Bleeding | Cancer | Cancer & Oncology | Cancer of the Uterus | Children | Chlamydia | Chronic Pain | Databases & Libraries | Diabetes | Disability | Eating Disorders & Weight Management | Endocrinology | Epistaxis (Nosebleeds) | Girls | Health | Health Management | Hormonal Therapy | Hormones | Hospital Management | Hospitals | Hyperthyroidism | Hypothyroidism | Ibuprofen | Learning | Lupus | Medical Ethics | Men | Mirena | Nutrition | OBGYN | Ovarian Cancer | Ovaries | Pain | Pain Management | Pediatrics | Polycystic Ovary Syndrome | Pregnancy | Skin | Sports Medicine | STDs | Study | Thyroid | Thyroid Cancer | Ultrasound | Universities & Medical Training | von Willebrand Disease | Women