Understanding Miralax: The parents’ guide on how to approach constipation

Increase water intake and exercise, adopt and maintain a fiber-rich diet and avoid foods that bind you. These are common ways to find relief from constipation. But sometimes a child needs more to keep the digestive “engines,” (or bowels) moving. To ease the discomfort of chronic childhood constipation, pediatricians often prescribe an over-the-counter laxative called Miralax, the brand name for the generic drug polyethylene glycol 3350. The odorless, tasteless powder is typically mixed with 8 ounces of water or other liquid-of-choice and prescribed to children for use once or twice daily. Common side effects include loose bowel movements and sometimes diarrhea, bloating or nausea. These side effects typically improve when dosing is adjusted. Miralax under the microscope However, Miralax has become a topic of discussion and scrutiny among pediatricians, parents and the media because it has not been FDA approved for use in children. Some parents worry about treating constipation because various websites have published misinformation about the side effects of medications to treat constipation. According to the North American Society for Pediatric Gastroenterology, Hepatology and Nutrition (NASPGHAN), an organization comprised of more than 1800 pediatric gastroenterologists nationwide, Miralax use appears to be free of serious side effects in most children. Boston Children’s Athos Bousvaros, MD, MPH, associate chief of Bos...
Source: Thrive, Children's Hospital Boston - Category: Pediatrics Authors: Tags: Diseases & conditions Source Type: news

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Purpose of review Opioids are potent drugs for the treatment of severe pain, but they are burdened by detrimental side-effects, such as respiratory depression, addiction, sedation and constipation. Their clinical application is undisputed in acute (e.g. perioperative) and cancer pain, but their use in chronic nonmalignant pain has met increasing scrutiny and has contributed to the opioid crisis. Thus, novel analgesics with reduced side-effects are badly needed. Recent findings Current research topics include enkephalinase inhibitors, allosteric and multivalent ligands, biased opioid receptor signaling and selective ac...
Source: Current Opinion in Supportive and Palliative Care - Category: Palliative Care Tags: PAIN: NON-MALIGNANT DISEASES: Edited by Anthony H. Dickenson and Kirsty Bannister Source Type: research
Abstract Neonatal tumors occur infrequently; sacrococcygeal teratoma (SCT) is a rare and abnormal mass often diagnosed on antenatal ultrasound. An SCT may cause serious antenatal complications, requires surgery in the neonatal period, and can lead to various long-term sequelae including fecal incontinence or constipation, urinary incontinence, and lower extremity mobility impairment. Even rarer are SCTs that include intraspinal extension necessitating complex neurosurgical intervention to relieve possible spinal cord compression or tumor tissue resection. A comprehensive understanding of the natural history of SCT...
Source: Neonatal Network - Category: Perinatology & Neonatology Authors: Tags: Neonatal Netw Source Type: research
Conclusion Recent advances in research on HTLV-1 provide better understanding of the molecular pathogenesis and mechanisms of HAM/TSP, and several clinical trials of novel therapies for patients with HAM/TSP have been initiated. However, long-term improvement of motor disability and quality of life still have not been achieved in HAM/TSP patients, and the clinical management remains challenging. Given that HAM/TSP is characterized by activated T-cells in both the periphery and CNS, studies in HAM/TSP will be highly informative for clarifying the pathogenesis of other neuroinflammatory disorders such as multiple sclerosis....
Source: Frontiers in Microbiology - Category: Microbiology Source Type: research
If you or a loved one have ever been hospitalized, you know that the primary focus of the hospital team is on diagnosing and treating the condition that put you in the hospital in the first place. The medical team works to treat a patient’s condition until the patient has improved enough to continue treatment and recovery out of the hospital. But recent findings have brought attention to an important issue that doesn’t strike until after you’ve left the hospital — post-hospital syndrome. What is post-hospital syndrome? Post-hospital syndrome can be defined as a period of vulnerability lasting up to ...
Source: Harvard Health Blog - Category: Consumer Health News Authors: Tags: Caregiving Health Healthy Aging Managing your health care Source Type: blogs
Tens of millions of Americans struggle to sleep at night, and many of them turn to sleeping pills for relief. Prescription and over-the-counter sleep aids are especially popular among older adults. A recent study published in the American Journal of Geriatric Psychiatry found that roughly one in three adults ages 65 to 80 use these drugs at least occasionally to fall asleep, and OTC meds like Benadryl and Tylenol PM are the pills of choice for sleepless seniors. Experts say this is concerning for a number of reasons. Studies have linked the regular, long-term use of OTC sleep medicines to some potentially serious side effe...
Source: TIME: Health - Category: Consumer Health News Authors: Tags: Uncategorized Baby Boomer Health sleep Source Type: news
ConclusionsThe increased research data and growing consumer awareness of the health benefits of kiwifruit provide logical motivation for their regular consumption as part of a balanced diet. Kiwifruit should be considered as part of a natural and effective dietary strategy to tackle some of the major health and wellness concerns around the world.
Source: European Journal of Nutrition - Category: Nutrition Source Type: research
CONCLUSIONS: This review demonstrates that antidepressant therapy may be more beneficial than placebo for the treatment of depression in PLWH. The low quality of the evidence contributing to this assessment and the lack of studies representing PLWH from generalized epidemics in low- to middle-income countries make the relevance of these finding in today's context limited. Future studies that evaluate the effectiveness of antidepressant therapy should be designed and conducted rigorously. Such studies should incorporate evaluation of stepped care models and health system strengthening interventions in the study design. In a...
Source: Cochrane Database of Systematic Reviews - Category: General Medicine Authors: Tags: Cochrane Database Syst Rev Source Type: research
BY SHANNON BROWNLEE On Wednesday, October 25, 2017 I was at the inaugural Society for Participatory Medicine conference. It was a fantastic day and the ending keynote was the superb Shannon Brownlee. It was great to catch up with her and I’m grateful that she agreed to let THCB publish her speech. Settle back with a cup of coffee (or as it’s Thanksgiving, perhaps something stronger), and enjoy–Matthew Holt George Burns once said, the secret to a good sermon is to have a good beginning and a good ending—and to have the two as close together as possible. I think the same is true of final keynotes aft...
Source: The Health Care Blog - Category: Consumer Health News Authors: Tags: OP-ED Patients Physicians Lown Institute Overtreatment Right Choice Alliance Shannon Brownlee Society for Participatory Medicine Source Type: blogs
AbstractIntroductionObstructed defecation syndrome (ODS) is a widespread and disabling syndrome. With this study, we want to evaluate the long-term results of stapled transanal rectal resection (STARR) performed with Contour Transtar device in the treatment for ODS. A re-evaluation of 113 patients subjected to STARR from June 2007 to January 2010 was conducted.MethodsAll the patients treated for symptomatic ODS with STARR with Contour Transtar were included in the study. We re-evaluate all patients treated in the study period with clinical examination and specific questionnaire to verify the stability of the functional res...
Source: World Journal of Surgery - Category: Surgery Source Type: research
Conclusion: It is extremely necessary for careful physical examination and detailed auxiliary examination to each system (including echocardiography, MRI, and so on) when diagnosing SIT. Also, recognizing and understanding the spectrum of situs anomalies is important, which aids in the diagnosis of disease and accordingly plan the therapeutic interventions.
Source: Medicine - Category: Internal Medicine Tags: Research Article: Clinical Case Report Source Type: research
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