Estimation of Glomerular Filtration Rate and Drug Dosing

The glomerular filtration rate (GFR) represents an index of kidney function and can be estimated (eGFR) by using various equations and/or formulas with markers such as inulin, iohexol, iothalamate, creatinine, cystatin C, and others.1 The GFR is the rate at which the glomerulus filters plasma and can be assessed from clearance. A good GFR is approximately ≥120 mL/min/1.73 m2, and represents the best overall assessment of kidney function.1,2 Assessment of the GFR is essential in clinical practice because the kidneys play important roles in metabolism and excretion of substances, blood pressure regulation, production of erythropoietin, regulation of acid-base, and maintain mineral and bone homeostasis.
Source: The Journal for Nurse Practitioners - Category: Nursing Authors: Tags: Prescription Pad Source Type: research