Effect of axitinib regulating the pathological blood-brain barrier functional recovery for glioblastoma therapeutics

CONCLUSION: The mechanism of axitinib involved in BBB functional regulation in the treatment of GBM is first illuminated in this report; moreover, this is the first report first referring to regulating pathological BBB functional recovery for GBM effective therapeutics. Overall, the view of regulating pathological BBB functional recovery may offer a novel sight for other CNS diseases relating to BBB permeability effective therapeutics.PMID:34967104 | DOI:10.1111/cns.13788
Source: CNS Neuroscience and Therapeutics - Category: Neuroscience Authors: Source Type: research