Prevalence of cystic metastases in a consecutive cohort of surgically removed branchial cleft cysts

CONCLUSION AND SIGNIFICANCE: When the investigation protocol for solitary cystic lesions of the neck is followed, the negative predictive value for malignancy is 97%. All adult patients with a cytologic verified diagnosis of branchial cyst should be examined with HPV-analysis of the cystic sample before excision of the cyst. Failure of predicting a malignancy is often associated with cytology of poor cellularity which may be improved by more frequent use of ultrasound guided fine-needle aspiration cytology (FNAC).PMID:34962438 | DOI:10.1080/00016489.2021.2016951
Source: Acta Oto-Laryngologica - Category: ENT & OMF Authors: Source Type: research