Activated Peripheral Blood B Cells in Rheumatoid Arthritis and Their Relationship to Anti –Tumor Necrosis Factor Treatment and Response: A Randomized Clinical Trial of the Effects of Anti–Tumor Necrosis Factor on B Cells

ConclusionOverall, our results support the notion that peripheral blood B cell subsets are remarkably stable in RA and not differentially impacted by dual blockade of TNF and LT with etanercept or single blockade of TNF with adalimumab. Activated B cells do associate with a less robust response.

Source: Arthritis and Rheumatology - December 28, 2021 Category: Rheumatology Authors: Nida Meednu, Jennifer Barnard, Kelly Callahan, Andreea Coca, Bethany Marston, Ralf Thiele, Darren Tabechian, Marcy Bolster, Jeffrey Curtis, Meggan Mackay, Jonathan Graf, Richard Keating, Edwin Smith, Karen Boyle, Lynette Keyes ‐Elstein, B Tags: Full Length Source Type: research