HLA-DR, -DP, -DQ expression status of parathyroid tissue as a potential parathyroid donor selection criteria and review of literature

CONCLUSION: Expression of HLA class II molecules in parathyroid cells appears to constitute a decisive factor. Despite the lack of clinical outcomes, present data proposes new insight with a detailed understanding of parathyroid immunogenicity. In the future, randomized controlled clinical trials are needed for the accurate assessment of the effect of the varied HLA class II expression profiles in parathyroid tissue.PMID:34955228 | DOI:10.1016/j.humimm.2021.12.003

Source: Human Immunology - December 27, 2021 Category: Allergy & Immunology Authors: Beyza Goncu Emrah Yucesan Yeliz Emine Ersoy Mustafa Erhan Aysan Nur Ozten Kandas Source Type: research