Kv7 channels critically determine coronary artery reactivity: left-right differences and down-regulation by hyperglycaemia
Conclusion
Our results reveal that the high expression and function of Kv7 channels in the LCA and their down-regulation by diabetes critically determine the sensitivity to key regulators of coronary tone.
Source: Cardiovascular Research - Category: Cardiology Authors: Morales-Cano, D., Moreno, L., Barreira, B., Pandolfi, R., Chamorro, V., Jimenez, R., Villamor, E., Duarte, J., Perez-Vizcaino, F., Cogolludo, A. Tags: Vascular biology Source Type: research
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