Does light at night pose a health risk?

Conclusion This opinion piece discusses the evidence related to whether exposure to electrical light night is a health risk. Much of the article considers various experimental studies where small numbers of participants were exposed to different light levels at night, as well as observational studies reportedly linking night-shift work with cancer, including breast and colon cancer. The researchers also identified some studies linking self-reported or measured light in the bedroom with depression and obesity. But this study has two prominent limitations. It does not appear to have been a systematic review. No methods are provided, and we do not know whether the researchers have searched the entire global literature on the subject to identify all relevant studies. We also do not know whether studies linking light at night with disease could have been preferentially discussed as examples, while other studies that did not find any links were either not identified or not discussed in this review. As such, this review must largely be considered to be the opinion of the researchers as informed by the evidence they looked at. The second limitation is the strength and quality of the evidence linking light exposure at night to disease. Most of the experimental studies discussed, where people were exposed to different light levels at night, were very small (one included 12 people, another eight). These results are specific to the small sample included. This means they may be...
Source: NHS News Feed - Category: Consumer Health News Tags: Lifestyle/exercise Cancer Source Type: news

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Publication date: Available online 18 January 2020Source: Clinica Chimica ActaAuthor(s): Guodong Zhao, Yong Ma, Hui Li, Shiming Li, Yun Zhu, Xiaoyu Liu, Shangmin Xiong, Yi Liu, Jin Miao, Sujuan Fei, Minxue Zheng, Xiangwei ZhaoAbstractBackgroundMethylated SFRP2 was previously reported as a non-invasive biomarker for colorectal cancer (CRC) detection with a relatively low sensitivity for early stage CRC. The purpose of this study was to evaluate the performance of a new plasma based CRC screening assay, SpecColon test, which tested methylated SFRP2 and SDC2 simultaneously in a single qPCR reaction, in detecting CRC and advan...
Source: Clinica Chimica Acta - Category: Laboratory Medicine Source Type: research
Conclusion: Advanced RCC has high morbidity and mortality with an increasing prevalence. Following tyrosine kinase inhibitors, checkpoint inhibitors have a great influence on treatment of advanced RCC, especially the combination of these two strategies. In 2019 these combined strategies demonstrated 5% complete remission with up to 60% objective response rate. While not immediately, but perhaps in the near future, advanced RCC will become a manageable chronic disease, even if a cure is not possible. PMID: 31942809 [PubMed - as supplied by publisher]
Source: Current Medical Research and Opinion - Category: Research Tags: Curr Med Res Opin Source Type: research
Authors: Oikonomou EK PMID: 31944137 [PubMed - as supplied by publisher]
Source: Expert Review of Molecular Diagnostics - Category: Laboratory Medicine Tags: Expert Rev Mol Diagn Source Type: research
Publication date: Available online 16 January 2020Source: Biosensors and BioelectronicsAuthor(s): Parvin Samadi Pakchin, Marziyeh Fathi, Hossein Ghanbari, Reza Saber, Yadollah OmidiAbstractIn the current study, we report on the design and development of a novel electrochemical immunosensor for the detection of cancer antigen 125 (CA125) oncomarker. Polyamidoamine/gold nanoparticles (PAMAM/AuNPs) were used to increase the conductivity and enhance the number of antibodies (Ab) immobilized on the electrode surface. Three-dimensional reduced graphene oxide-multiwall carbon nanotubes (3DrGO-MWCNTs) were used to modify the glass...
Source: Biosensors and Bioelectronics - Category: Biotechnology Source Type: research
The Redwood City company raised $226 million in three venture rounds after its formation five years ago by Third Rock Ventures.
Source: bizjournals.com Health Care:Biotechnology headlines - Category: Biotechnology Authors: Source Type: news
This study examined the prevalence of cyberbullying among adolescent psychiatric inpatients and related it to social media usage, current levels of symptoms, and histories of adverse early life experience. METHODS: Data on the prevalence of social media utilization and cyberbullying victimization were collected from adolescent psychiatric inpatients aged 13 to 17 years from September 2016 to April 2017. Fifty adolescent psychiatric inpatients completed 2 surveys assessing childhood trauma (the Trauma Symptom Checklist for Children and the Childhood Trauma Questionnaire) and the Cyberbullying Questionnaire. RESULTS:...
Source: Journal of Clinical Psychiatry - Category: Psychiatry Tags: J Clin Psychiatry Source Type: research
This study examines temporal relationships between 3 dimensions of social support (social connectedness, dyadic satisfaction, and perceived support), and psychological distress in a sample of NG/R spouses during the first year after a service member returns from deployment. Data from 103 military spouses were drawn from a larger intervention development study. Autoregressive cross-lagged panel analyses examined the stress-buffering and support erosion hypotheses over a 3-month period. DRS were measured by the cumulative number of deployments and duration of most recent deployment. Distress was assessed using latent variabl...
Source: The American Journal of Orthopsychiatry - Category: Psychiatry Tags: Am J Orthopsychiatry Source Type: research
Authors: Herring WJ, Ceesay P, Snyder E, Bliwise D, Budd K, Hutzelmann J, Stevens J, Lines C, Michelson D Abstract INTRODUCTION: We evaluated the clinical profile of the orexin receptor antagonist suvorexant for treating insomnia in patients with mild-to-moderate probable Alzheimer's disease (AD) dementia. METHODS: Randomized, double-blind, 4-week trial of suvorexant 10 mg (could be increased to 20 mg based on clinical response) or placebo in patients who met clinical diagnostic criteria for both probable AD dementia and insomnia. Sleep was assessed by overnight polysomnography in a sleep laboratory. The primar...
Source: The Journal of Alzheimers Association - Category: Psychiatry Tags: Alzheimers Dement Source Type: research
CONCLUSION: According to the high percentage of patients diagnosed with vision-threatening DR in this study, an early diagnosis of this complication of diabetes seems to be important. Teleophthalmology enhances patient accessibility to the healthcare system, making early diagnosis of DR easier, with a high degree of satisfaction among patients and healthcare professionals. PMID: 31941342 [PubMed - in process]
Source: Rural and Remote Health - Category: Rural Health Tags: Rural Remote Health Source Type: research
Publication date: Available online 16 January 2020Source: Journal of Hazardous MaterialsAuthor(s): Reshu Chauhan, Surabhi Awasthi, Yuvraj Indoliya, Abhishek Singh Chauhan, Shashank Mishra, Lalit Agrawal, Sudhakar Srivastava, Sanjay Dwivedi, Poonam C. Singh, Shekhar Mallick, Puneet Singh Chauhan, Veena Pande, Debasis Chakrabarty, Rudra Deo TripathiAbstractArsenic (As), a chronic poison and non-threshold carcinogen, is a food chain contaminant in rice, posing yield losses as well as serious health risks. Selenium (Se), a trace element, is a known antagonist of As toxicity. In present study, RNA seq. and proteome profiling, a...
Source: Journal of Hazardous Materials - Category: Environmental Health Source Type: research
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