The activation of complement C1q and C3 in glomeruli may accelerate the progression of diabetic nephropathy: evidence from transcriptomic data and renal histopathology

ConclusionsComplement activation is involved in the development of DN, and activation of the classical complement pathway in glomeruli may accelerate disease progression.

Source: Journal of Diabetes Investigation - December 21, 2021 Category: Endocrinology Authors: Yuanyuan Jiao, Shimin Jiang, Ying Wang, Tianyu Yu, Guming Zou, Li Zhuo, Wenge Li Tags: ORIGINAL ARTICLE Source Type: research