Association between peripheral blood WBCs C3aR mRNA level and plasma C3a, C3aR, IL-1 β concentrations and acute exacerbation of chronic obstructive pulmonary disease

CONCLUSION: The peripheral blood WBCs C3aR mRNA and plasma C3a, C3aR, and IL-1β in COPD patients were significantly related to the risk of disease deterioration. The C3a-C3aR axis may be involved in airway inflammation in patients with COPD.PMID:34923262 | DOI:10.1016/j.imbio.2021.152164
Source: Immunobiology - Category: Allergy & Immunology Authors: Source Type: research