Diabetic ketoacidosis in pregnancy- Case series, pathophysiology, and review of the literature

Diabetic ketoacidosis (DKA) during pregnancy is a life-threatening emergency for both the mother and the fetus. The pathophysiology of DKA in pregnancy has its own characteristics due to multiple factors, such as insulin resistance, accelerated starvation and respiratory alkalosis, thus creating ketosis-prone state, with DKA occurring at milder degrees of hyperglycemia, even in normoglycemic levels, which can result in delayed diagnosis and treatment with potential for adverse metabolic consequences.

Source: European Journal of Obstetrics, Gynecology, and Reproductive Biology - December 20, 2021 Category: OBGYN Authors: Tamar Eshkoli, Leonid Barski, Yaniv Faingelernt, Alan Jotkowitz, Alona Finkel-Oron, Dan Schwarzfuchs Source Type: research